When the treatment doesn’t work: what predicts difficult-to-treat postpartum depression?

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Swedish nationwide study of 58,618 women found 6% experienced treatment-resistant postpartum depression. Risk factors included lower socioeconomic status, smoking, pre-existing health conditions, caesarean or preterm birth.

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Prevention, screening and treatment of peripartum depression for women: new clinical guidelines

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International group developed 44 evidence-based recommendations for peripartum depression, supporting psychological interventions and universal screening with clear referral pathways.

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How to deliver trauma-informed perinatal mental healthcare

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One in four women experience mental health difficulties during the perinatal period, yet trauma often goes unrecognised. This new review highlights eight clear recommendations for trauma-informed care and reminds us that creating safe, compassionate spaces may matter more than any new intervention.

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Bundle of joy, bundle of nerves: What do we really know about postpartum anxiety?

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Postpartum anxiety affects more than 1 in 10 new mothers worldwide, yet researchers still can’t agree on how to define or measure it. This new review in The Lancet Psychiatry takes stock of what we know so far and why the field urgently needs consensus.

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Is it a gut feeling? How the microbiome may shape perinatal mental health in women with higher body weight

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What if perinatal mental health started in the gut? New research from Finland suggests certain bacteria may be associated with depressive and anxiety symptoms during pregnancy and after birth, raising questions about inflammation, causality, and the future of microbiome-based screening and treatment.

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Circle of Security under scrutiny: NHS trial finds no added benefit for perinatal mental health

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A large NHS trial found that the Circle of Security parenting programme did not outperform treatment-as-usual for parents experiencing perinatal mental health difficulties. But does this mean we should stop offering it?

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Perinatal resilience: a protective factor or a misunderstood measure?

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More than 1 in 5 women experience mental health difficulties during pregnancy or after birth. Could boosting resilience help prevent mental health problems during and after pregnancy? This systematic review investigates the evidence, limitations, and implications for practice.

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Culturally adapted CBT may lead to recovery from postnatal depression in British South Asian women

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Angelica Tong explores the ROSHNI-2 trial of a culturally adapted CBT programme for postnatal depression in British South Asian women.

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New research on metabolomic pathways supports the case to routinely screen for antenatal depression

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Nora Rosenberg summarises the largest and most comprehensive study to date on metabolomic pathways to antenatal depression, birth outcomes and offspring development.

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Psychotropic medication during pregnancy: new umbrella review finds no convincing evidence of adverse health outcomes for the baby

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Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy.

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