Oral Cancer: Elective neck dissection or watch and wait?

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

There is an ongoing debate about the management of patients with oral cavity squamous cell carcinoma and clinically negative cervical lymph nodes. Some clinicians favour preventive elective neck dissection (END) which although is linked with favourable survival has an adverse effect on quality of life while others adopt a wait and watch policy. The aim [read the full story…]

Ameloblastoma: Radical or conservative surgery?

CT_Scan_of_ameloblastoma

20 retrospective studies were included in this review of surgical approaches for ameloblastoma . The finding suggest fewer recurrences with radical approaches.

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Mouth and throat cancer: evidence for best surgical approaches uncertain

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.

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Limited evidence suggests that co-morbid chronic physical illness may not increase risk for recurrence in depression

Depression

There is a widespread clinical presumption that people who have both major depressive disorder (MDD) and a co-morbid chronic physical illness represent a ‘double trouble’ group. This leads to the expectation that the depression prognosis for these people would be poor with increasing likelihood of recurrence. Evidence supports the view that depression is prevalent among [read the full story…]

Cochrane review cannot support training to recognise early signs of recurrence in schizophrenia due to low quality evidence

man staring at piles of paper

NICE Guidelines state that around three quarters of people with a diagnosis of schizophrenia experience a chronic illness: with recurrent episodes of remission and relapse.  One way that chronic physical health conditions, such as diabetes and heart disease, are managed is by using early warning signs (EWS) training and this prevention strategy is now often [read the full story…]

keratocystic odontogenic tumour recurrence rates

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The keratocystic odontogenic tumour (KCOT, odontogenic keratocyst (OKC)) was first described in the literature in 1956 and is classified by the World Health Organization classified as a benign odontogenic tumour. It is generally accepted that they arise from the remnants of the dental lamina and are benign but locally aggressive and tend to reoccur.  They [read the full story…]