A large Australian study suggests that atypical depression is genetically, metabolically and clinically distinct, with poorer response to SSRIs and SNRIs.
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Study of 3 million Australian adults prescribed opioids, 84% of self-harm events and 81% of suicides didn’t involve opioids. Challenges belief that prescribing increases self-harm risk.
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Men are around 3 times more likely to die by suicide than women, and new evidence suggests relationship breakdowns could be a key risk factor. A major 2025 meta-analysis explores the complex links between separation, divorce, and suicidality in men.
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Depression, anxiety, and suicidality are higher among LGBTQ+ workers, especially in hostile or unsupportive workplaces. But are research and policy keeping up? This new review sets out the case for change.
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People with psychosis face unique risks around suicide, but most treatments aren’t designed with them in mind. This new RCT tested a targeted therapy that tackles those specific challenges. So what did it find?
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Laura Melzer considers a qualitative review of client and therapist perspectives on the therapeutic alliance in the context of psychotherapy for suicidal feelings.
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Ellie Davis highlights a retrospective cohort study that explored eating disorder treatment outcomes between transgender, gender diverse and cisgender adolescents.
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Derek de Beurs explores a meta-analysis which finds that randomised controlled trials of psychological interventions for depression rarely report assessments of suicide.
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A group of MSc students from UCL summarise a study examining the links between antipsychotics, risk of violent crimes and suicidal behaviour in people diagnosed with a ‘personality disorder’.
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Filip Marzecki summarises a large-scale systematic review and meta-analysis investigating prevalence and odds of bullying involvement in young people with mental health and neurodevelopmental conditions.
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