Third molars: Regenerative techniques for preventing periodontal defects

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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.

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People with severe mental illness have more adverse outcomes from medical or surgical treatment

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Laoise Renwick considers the findings of a recent systematic review on the safety of service users with severe mental illness receiving inpatient care on medical and surgical wards.

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Few adverse events with single dose oral analgesics for acute postoperative pain

This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.

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Intravenous midazolam sedation for dental treatment: review found no significant side effects

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This review of IV midazolam for treating children and adolescents only identified 11 studies (5 RCTs, 6 non randomised). No serious adverse events were reported but there was a generalised inconsistency in side effect reporting. Consequently the call for better side effect reporting.

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