This review of botulinum toxin (BTX) in the management of temporomandibular joint disorders (TMD) included 7 small RCTs of low quality. high quality well reported RCTs with larger sample sizes and longer follow times are needed to properly assess the effectiveness of BTX in the management of TMD.
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Sally McManus writes her debut elf blog on a recent national cohort study of multiple adverse outcomes following first discharge from psychiatric care, which finds that mental health inpatients are more likely to experience all types of adversity after leaving hospital.
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This review of the the effectiveness of different antibiotic protocols to prevent early dental implant failure includes 9 RCTs showing that antibiotics were protective against early implant failures.
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Two surgical approaches ( open and closed) for palatally displaced canines were compared in this multi-centre RCT. No differences in operating time was seen between the two approaches but those in the open group had more pain.
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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.
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Laoise Renwick considers the findings of a recent systematic review on the safety of service users with severe mental illness receiving inpatient care on medical and surgical wards.
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This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.
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This review of IV midazolam for treating children and adolescents only identified 11 studies (5 RCTs, 6 non randomised). No serious adverse events were reported but there was a generalised inconsistency in side effect reporting. Consequently the call for better side effect reporting.
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