Using the highs to combat the lows: ketamine-assisted therapy for anxiety and depression

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In her debut blog, Gabrielle Williams reviews a US study on the safety and effectiveness of ketamine-assisted therapy (a digital intervention combining psychotherapy, journaling and ketamine) for moderate to severe anxiety and depression.

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Long-term psychoanalytic psychotherapy for treatment-resistant depression: not cost-effective compared to treatment as usual

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In her debut blog, Ella Tuominen considers the Tavistock Adult Depression Study (TADS), which evaluated the cost-effectiveness of long-term psychoanalytic psychotherapy for treatment resistant depression compared to treatment as usual.

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Everyday discrimination during the COVID-19 pandemic: the toll on mental health

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A group of UCL MSc students summarise a US study on the association of everyday discrimination with depression and suicidal ideation during the pandemic.

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Psilocybin for ‘treatment-resistant depression’: an island of hope in an ocean of uncertainty?

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In this blog, UCL MSc students consider an RCT published in the New England Journal of Medicine, which suggests that psilocybin-assisted psychotherapy may help reduce depression in people with severe and enduring illness, but side effects are common and more research is needed to look into longer term effects.

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Parents’ depression can be linked to children’s emotional difficulties

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Lisa Lloyd summarises a new paper in the BJPsych, which focuses on parental depression symptoms in both mothers and fathers, and how they are linked with emotional difficulties in their children.

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Detection of depression in primary care settings in low- and middle-income countries

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Lucy Barrass considers a systematic review exploring the detection of depression in primary care settings in low- and middle-income countries.

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Is cognitive behavioural therapy the best we’ve got for depression?

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Camilla Babbage and Maria Loades summarise the largest meta-analysis to date on the effectiveness of CBT for depression.

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Adolescent depression is not the same as adult depression: new systematic review focuses on adolescents’ lived experiences

How are we currently supporting adolescents presenting with depression in clinical practice? Are we tailoring our approach, or are we treating them like mini adults?

Nina Higson-Sweeney reflects on the findings of a recent systematic review looking at the lived experience of adolescent depression, which has important implications for anyone supporting young people at risk of depression.

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Body weight and perinatal depression: what’s the link?

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In her debut blog, Sarah Nicholson summarises a systematic review of pre-pregnancy BMI and the risk of antenatal and postnatal depression.

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Aerobic exercise for major depression: the role of reward processing and cognitive control

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Francesca Bentivegna summarises a trial which looks at how aerobic exercise can help students with major depression by examining reward and cognitive control as predictors and treatment targets.

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