Magic mushrooms promising for treatment resistant depression

Psilocybin

Our #EvidenceLive team of bloggers report on a recent feasibility study of psilocybin for the treatment of refractory depression.

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Mindfulness-based cognitive therapy can prevent recurrent depression

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Sarah McDonald reports on a meta-analysis published yesterday, which found that when compared with active treatment, mindfulness-based cognitive therapy resulted in a reduced risk of depressive relapse.

This blog also features a podcast interview with the lead author of the research, Professor Willem Kuyken.

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Long-term psychoanalytic psychotherapy for treatment-resistant depression

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Sarah McDonald presents the results of the Tavistock Adult Depression Study; a pragmatic RCT of long-term psychoanalytic psychotherapy for treatment-resistant depression.

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Cognitive therapies for depression in adults: let’s just stick to the facts

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Ioana Cristea reviews the NIHR-DC Highlight on cognitive therapies for depression, published online today, which summarises three NIHR-funded trials (REEACT, CoBalT and PREVENT) looking at cCBT, CBT and MBCT for depression in adults.

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Aripiprazole for treatment-resistant depression in older adults

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Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.

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CBT plus medication for treatment-resistant depression: the CoBalT RCT long-term follow-up

In February 2016 we blogged CoBalT and concluded that CBT plus usual care (including antidepressants) is clinically and cost effective in the long-term for people whose depression has not responded to medication.

Sarah McDonald considers the findings of the CoBalT RCT long-term follow-up, which finds that CBT plus antidepressants are clinically and cost effective for treatment-resistant depression in primary care.

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