Sodium lauryl sulphate (SLS): Does SLS-free toothpaste use benefit patients with recurrent aphthous stomatitis

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This review of the effects of sodium lauryl sulphate (SLS) free and SLS-containing toothpastes in patients with recurrent aphthous stomatitis (RAS) included 4 small RCTs with the findings suggesting that patients with RAS may benefit from using SLS-free toothpaste. However the quality of teh availabel studies is very low.

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Behçet’s disease: review found insufficient evidence to support or refute interventions for oral ulceration

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This review focuses on the treatment of oral ulceration in Behçet’s disease, 15 trials examining 13 different interventions were found. There was insufficient evidence to support or refute the use of any included intervention with regard to pain, episode duration, or episode frequency associated with oral ulcers, or safety of the interventions.

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Small study suggests possible role for low-level laser therapy in treating recurrent oral ulcers

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Recurrent aphthous stomatitis (RAS) is the most common form of oral ulceration. Prevalence rates for the general population vary between 5-60%. Onset generally peaks between the ages of 10-19 an often persists in to adulthood. A wide range of topical and systematic treatments have been utilised including low-level laser therapy. The aim of the study [read the full story…]

New Cochrane Protocol March 2014

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The latest Cochrane protocol from the Oral Health Group to be published is planning to look at the clinical effectiveness and safety of interventions in the pain, episode duration and episode frequency of oral ulcers and any change in the quality of life for patients with aphthous-type ulceration associated with Behçet’s disease. Behçet’s disease is [read the full story…]

Guidance on the management of acute dental problems from SDCEP

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The Scottish Dental Clinical Effectiveness Programme (SDCEP) has recently launched guidance for the management of patients with acute dental problems. The scope of the guidance is to:- Encourage a consistent approach to the management of acute dental problems to reduce avoidable variation in practice Improve the quality of unscheduled clinical care for patients with acute [read the full story…]

Study shows that berberine had a positive effect on recurrent aphthous ulceration

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Recurrent aphthous stomatitis (RAS) is usually episodic and self-limiting but can produce severe ulcers that interfere with eating speaking and swallowing.  Minor RAS  (MiRAS) is the most common form.  The aim of this trial was to investigate the efficacy and safety of berberine (an isoquinoline alkaloid originally isolated from medicinal herbs) in the treatment of [read the full story…]

No single systemic treatment was found to be effective for treatment of mouth ulcers

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The prevalence of mouth ulcers (recurrent aphthous stomatitis , RAS) has been estimated at between 5 – 60%. They can be painful and slow to heal.  There are three recognized forms; minor, major and herpetiform.  The peak age at onset is between 10 and 19 years of age but they can persist through adulthood. The [read the full story…]

No well-designed studies of topical agents for treatment of HIV-related oral ulcers

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Oral Ulcers occur more frequently, last longer and produce more painful symptoms in HIV-infected adults. Aphthous ulcers are generally classified as major, minor or herpetiform. Major ulcers can exceed 3cm in diameter and can develop into large necrotic lesions. Major ulcers are seen more commonly in HIV-infected than non-infected adults.  The aim of this Cochrane [read the full story…]

Study shows dexamethasone ointment had positive effect on recurrent aphthous ulceration

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Yesterday we looked at a study that looked at multivitamins for the treatment of recurrent aphthous stomatitis (RAS). Today we have another study whose aim was to explore the efficacy and safety of dexamethasone ointment in the treatment of RAS.  What did they do This was a multi-centre trail conducted across 5 centres in China. [read the full story…]

Stress associated with onset of recurrent mouth ulcers

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Recurrent aphthous stomatitis (RAS) is a common and painful oral disease. It is characterised by recurring mucosal ulceration in an otherwise healthy individual.  Its prevalence is commonly estimated to be between 5% and 25%  with a peak age of onset between 10 and 19 years although they may continue throughout the patient’s life span.  An [read the full story…]