Nicotine replacement therapy – oral side effects

For inpatients with psychiatric symptoms of moderate severity, the study suggests those using nicotine inhalers were most successful overall in their quit attempts. There were no severe adverse reactions to the NRTs.

This review of the evidence on possible association between locally delivered nicotine replacement therapy(NRT) and oral side effects included 28 RCTs. Most of the RCTs were at high risk of bias mainly because of allocation concealment concerns. Reported oral side effects including oral soreness, gastric reflux or vomiting, and mouth or throat irritation.

[read the full story...]

Vitamin B for the treatment of mouth ulcers

12775934043_e5394ce13b_o

This review of the efficacy of vitamin B in treating mouth ulcers included 16 RCTs published since 2010. All the included studies were published in Chinese with the findings that treatment was more effective in patients treated with vitamin B.

[read the full story...]

Sodium lauryl sulphate (SLS): Does SLS-free toothpaste use benefit patients with recurrent aphthous stomatitis

shutterstock_89901511

This review of the effects of sodium lauryl sulphate (SLS) free and SLS-containing toothpastes in patients with recurrent aphthous stomatitis (RAS) included 4 small RCTs with the findings suggesting that patients with RAS may benefit from using SLS-free toothpaste. However the quality of teh availabel studies is very low.

[read the full story...]

Cochrane Protocols December 2013

shutterstock_74352844

Shortly before Christmas two new protocols for Cochrane review from the Oral Health Group appeared on the Cochrane Library. The first one is:- Taylor J, Brocklehurst P, Glenny AM, Walsh T, Tickle M, Lewis MA, Riley P, Yates JM, Pemberton MN. Topical interventions for recurrent aphthous stomatitis (mouth ulcers) (Protocol). Cochrane Database of Systematic Reviews [read the full story…]

Study shows that berberine had a positive effect on recurrent aphthous ulceration

shutterstock_96140129

Recurrent aphthous stomatitis (RAS) is usually episodic and self-limiting but can produce severe ulcers that interfere with eating speaking and swallowing.  Minor RAS  (MiRAS) is the most common form.  The aim of this trial was to investigate the efficacy and safety of berberine (an isoquinoline alkaloid originally isolated from medicinal herbs) in the treatment of [read the full story…]