Risk factors for depression relapse while on long-term maintenance antidepressant treatment

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In her debut blog, Asha Ladwa discusses a secondary analysis of data from the ANTLER trial, which investigated the clinical factors associated with relapse in primary care patients on long-term maintenance antidepressants.

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What’s the relationship between stressful life events and psychosis?

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Kris Deering considers a 2-year prospective observational study published in the Lancet Psychiatry which found strong links between stressful life events and relapse in first-episode psychosis.

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Antidepressant withdrawal or depression relapse? International guidelines on antidepressant discontinuation are unclear

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Adele Framer summarises a systematic review which finds that major guidelines on antidepressant discontinuation only give clinicians vague guidance on distinguishing withdrawal from relapse.

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Schizophrenia and cannabis use: new evidence measures risk of relapse

Over 20% of cannabis users experience a psychotic relapse within 24 months of treatment.

In her debut blog, Sally Turner considers a recent study on cannabis use and clinical outcomes in people with first-episode schizophrenia spectrum disorders over 24 months of treatment.

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Antidepressant discontinuation and continuation: new Cochrane review finds miasma of confound

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Adele Framer, Founder of SurvivingAntidepressants.org, explores a recent Cochrane review on antidepressant discontinuation versus continuation for adults with depression or anxiety, which highlights huge uncertainty in the science about antidepressant withdrawal.

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Bipolar disorder and distress: systematic review of first-person accounts

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A group of UCL Mental Health Masters Students summarise a meta-synthesis of qualitative research, which looks at what people diagnosed with bipolar disorder experience as distressing.

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Which personality traits may protect us from alcohol use disorder?

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Andrew Jones summarises a recent systematic review and meta-analysis of alcohol treatment outcome, which identifies a range of personality traits that are associated with relapse.

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Anorexia nervosa: relapse, remission and recovery

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Sarah McDonald asks: What happens after treatment? She summarises a recent systematic review of relapse, remission, and recovery in anorexia nervosa.

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Cannabis use can lead to relapse in psychosis, partially because patients stop taking medication

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Thomas Richardson writes his debut blog about a recent prospective analysis of poor medication adherence and risk of relapse associated with continued cannabis use in patients with first-episode psychosis.

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Class II malocclusion- what factors predict sagittal stability after treatment?


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Factors affecting relapse after treatment of class II malocclusion was investigated in this review. Only 17 retrospected studies met the review criteria providing limited evidence to support the influence of factors predictive of sagittal stability following orthodontic treatment.

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