Improving antidepressant outcomes: what works for whom and why?

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Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.

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The Lancet Psychiatry Commission on psychological treatments #SeeingFurther

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Ioana Cristea highlights some of the key ideas from the recently published Lancet Psychiatry Commission on psychological treatments research in tomorrow’s science. She also raises a number of objections to the 50-page report, which we hope will generate some much needed discussion on this topic.

Look out for our #SeeingFurther podcast with the authors of the Commission and a Twitter chat at 12:30pm GMT on Monday 19th March.

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Is mental malaise the psychological equivalent of obesity?

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Stan Kutcher reflects on a recently published briefing paper entitled: mental ill-health among children of the new century, which concluded that one in four 14 year old girls had self-reported “high symptoms of depression”.

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Memory lane: the road to recovery in depression?

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Becci Strawbridge explores a prospective cohort study that looks at variation in the recall of socially rewarding information and depressive symptom severity.

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Trajectories of depressive symptoms in children and adolescents

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Jess Bone on a systematic review of longitudinal studies, which explores the different trajectories of depressive symptoms in children and adolescents, and the factors that might help predict or protect young people.

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Periodontal disease – patient awareness levels low

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Six cross sectional and community-based studies involving a total of 7945 patients were included in this review. While awareness and knowledge of periodontal disease was found to be low the quality of the available studies was not high.

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Prognosis of brief psychotic episodes

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Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.

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What do you want from your psychiatric medication?

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John Baker presents a systematic review of preferences for medication-associated outcomes in mental disorders, which concludes that we just don’t know what value mental health service users place on the different outcomes that come from taking psychiatric medication.

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Experience sampling and ecological momentary assessment for studying anxiety disorders

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Alan Underwood publishes his debut Mental Elf blog on a narrative review of experience sampling and ecological momentary assessment for studying the lives of people with anxiety disorders.

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Diagnostic test accuracy of first rank symptoms for schizophrenia

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Raphael Underwood summarises a recently updated Cochrane systematic review, which aimed to systematically evaluate the accuracy of first rank symptoms for diagnosing schizophrenia.

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