Oral cancer detection: Limited evidence for use of chemiluminescence and autofluorescent imaging devices in primary care

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Early detection of oral cancer improves prognosis so methods to improve diagnosis are welcome. The review we look at today looks at two light-based systems: chemiluminescence or autofluorescence. 25 studies were included and they are well summarised but few were tested in primary care. Neither system provided much improvement on the level of sensitivity and specificity achieved by conventional oral examination. Therefore it is suggested that these tools are better suited to specialist clinics in which there is a higher prevalence of disease and where experienced clinicians may better discriminate between benign and malignant lesions.

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Some evidence for the presence of hepatitis viruses A, B and C in oral fluids

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Viral hepatitis is caused by five distinct viruses (A-F) and they represent a significant worldwide healthcare problem. Three of the viruses hepatitis A, B and C (HAV, HBV, HCV) are the most common causes. Recently, there has been renewed interest in whether oral fluids can be considered as a source of viral hepatitis transmission.  There [read the full story…]