Just how good are antipsychotics at preventing relapse? Bridging the efficacy-effectiveness gap

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Samei Huda summarises a new network meta-analysis in the Lancet Psychiatry on the efficacy and effectiveness of antipsychotics for schizophrenia in research settings, such as randomised controlled trials, versus real-world and clinical settings.

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Individual, group and guided self-help CBT for panic disorder: most delivery formats equally effective, but more evidence needed

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Hannah Wallace summarises a network meta-analysis comparing four different formats of CBT for panic disorder, which finds “no efficacy differences between CBT delivered as guided self-help, or in the face-to-face individual or group format in the treatment of panic disorder”.

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Towards better psychological treatment of depression #DepressionSolvingTheToll part 3

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Part 3 in a four-part series on solving the toll of depression on populations. Pim Cuijpers focuses on the psychological treatment of depression and gives an overview of a meta-analytic research domain.

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Blood-based inflammatory markers in acute vs chronic schizophrenia

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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

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Alveolar ridge- soft tissue preservation techniques

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In hwer first blog for the Dental Elf Aljeeta Kadam looks at a review aiming to evaluate and compare different alveolar ridge preservation techniques.

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To stay on antipsychotics or not to stay on antipsychotics? A longstanding question with an update

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Joe Pierre considers a recent network meta-analysis on continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable.

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Burning mouth syndrome treatments – network meta-analysis

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This review of all treatments for the relief of pain associated with burning mouth syndrome (BMS) as compared with no intervention or placebo included 44 RCTs. There was moderate certainty evidence that clonazepam is likely to reduce the pain of BMS compared with placebo.

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Youth mental health interventions: umbrella review presents efficacy and acceptability data

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In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.

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Treating PTSD in adults: EMDR and trauma-focused CBT still lead the way

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Nada Abou Seif summarises a network meta-analysis which finds that EMDR and trauma-focused CBT remain the most effective ways to treat adult PTSD.

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New evidence on treatments for symptoms of depression in dementia

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Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.

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