Psychotherapy and antidepressant tapering can help people at risk of depression relapse, but more evidence needed before we can provide personalised treatment

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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.

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Self-stigma and depression amongst sexual minorities: can mindfulness help?

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Brendan Dunlop summarises a recent Chinese cross-sectional study, which looks at how mindfulness may be useful in reducing self-stigma and depressive symptoms in lesbian, gay and bisexual people.

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Repetitive negative thinking: an important clinical target for the treatment of depression and anxiety? #ActiveIngredientsMH

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Imogen Bell summarises a systematic review relating to her own Wellcome Trust funded research into repetitive negative thinking in anxiety and depression.

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Universal interventions to prevent mental illness in medical students

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Tayla McCloud summarises a systematic review and meta-analysis on the effectiveness of universal programmes for the prevention of suicidal ideation, behaviour and mental ill health in medical students.

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Psychotherapy for adult depression: is it as good as it’s cracked up to be?

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Ellie Gant summarises a meta-analysis that asks: Was Eysenck right after all? A reassessment of the effects of psychotherapy for adult depression. The paper suggests that we seriously overestimate the benefits of psychotherapy by including biased trials in meta-analyses, and that there’s insufficient reliable research to be certain about the effectiveness of problem-solving therapy, interpersonal psychotherapy and behavioural activation.

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Is third-wave CBT good value?

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Chris Sampson summarises a systematic review on the economic impact of third-wave cognitive behavioural therapies, such as mindfulness-based cognitive therapy, acceptance and commitment therapy, extended behavioural activation, dialectical behaviour therapy, and mindfulness-based stress reduction.

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Third wave CBT for psychosis: how reliable is current evidence?

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Keith Laws explores a recent meta-analysis of third wave CBT for psychosis, which suggests we need better evidence about the safety and efficacy of mindfulness, acceptance-based therapy, compassion-focused therapy and other third wave approaches.

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Third wave psychotherapies for depression and anxiety in older people

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Sarah McDonald is left feeling frustrated by this meta-analysis of mindfulness-based cognitive therapy and acceptance and commitment therapy for depression and anxiety in older people.

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