Kirsten Lawson summarises a new ‘state of the art review’ in the BMJ which focuses on novel and emerging pharmacotherapy and neuromodulation for people with ‘treatment resistant depression’.
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In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.
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Amelia Talbot reviews a qualitative meta-synthesis on the long-term effects of Electroconvulsive Therapy (ECT) reported by people who have received it.
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Dean Connolly looks at an international study which asks: Is there consensus across evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?
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Andrew Shepherd reports on a post-hoc analysis of pre-existing trial data, which does little to convince him that ECT is a safe and effective treatment option for older people with severe depression.
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Bipolar disorder features as one of the top ten disabling disorders for working age adults. There are numerous risks including suicide, increased mortality and reduced social functioning associated with the disorder. Key to enabling recovery is preventing acute episodes from occurring, with each episode increasing the risk of future ones. Therefore ensuring long-term maintenance treatment [read the full story…]
The BMJ have published an up to date guideline on the treatment of depression with drugs and physical interventions. It provides a good overview of the effectiveness and safety of antidepressants, electroconvulsive therapy, exercise, lithium augmentation, pindolol augmentation, and St John’s wort. The authors found 88 systematic reviews, RCTs, or observational studies and performed a [read the full story…]
