Antidepressants don’t help with many cognitive impairments, even when they do improve mood

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Lucas Shelemy on a recent randomised longitudinal study that explores the effect of antidepressant treatment on cognitive impairments associated with depression.

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What is the evidence for evidence-based guidelines?

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Andrew Shepherd returns to the woodland with a blog about the evidence-practice gap in specialist mental healthcare; highlighting a recent systematic review and meta-analysis of guideline implementation studies.

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Maternal anxiety disorders in the postnatal period: what do we know?

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Janes Iles and Annette Eneberi summarise a recent systematic review and meta-analysis of current research evidence on anxiety disorders and their prevalence amongst postpartum women.

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A social model for understanding madness and distress

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Alison Faulkner on a new Shaping Our Lives report, which addresses service user and survivor views about ways of understanding madness and distress, but in particular about the potential of a social model.

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Lithium for bipolar disorder: the best maintenance mood stabiliser protection against self-harm and suicide?

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Michael Ostacher provides a robust appraisal of a recent UK cohort study that suggests bipolar disorder patients taking lithium had reduced self-harm and unintentional injury rates, when compared with patients taking valproate, olanzapine or quetiapine.

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Adding antidepressants to antipsychotics in schizophrenia: do they work, for what, and are they safe?

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Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.

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Have the EAGLES landed? Safety of varenicline, bupropion and NRT in smokers with and without mental illnesses

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Paul Christiansen presents the results of the EAGLES RCT into the neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patches in smokers with and without psychiatric disorders.

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The Two Pots? Experiences of peer workers within mental health services

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Sarah Carr examines a literature review on peer workers’ perceptions and experiences to the implementation of peer worker roles in mental health services, and finds some familiar themes.

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The vexing challenge of suicide prevention: a research informed perspective on a recent systematic review

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Stanley Kutcher and Yifeng Wei provide an in-depth analysis of a recent systematic review of suicide prevention strategies.

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Alcohol use disorder and increased mortality

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Matt Field summarises a recent Swedish longitudinal cohort study of alcohol use disorder and mortality across the lifespan. This study quantifies the environmental and genetic risk factors that contribute to increased mortality in people with alcohol use disorder.

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