Samei Huda

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Dr Samei Huda has been working as a Consultant Psychiatrist for over 12 years including a year in Australia. He also completed a Diploma in Cognitive Therapy (though he doesn’t see patients for therapy) and a Master of Science in Psychiatry. He has been working with an Early Intervention in Psychosis team since 2007. Over his career he has directly assessed, managed and treated hundreds of patients with psychosis of different types. He recommends people with an interest in psychosis to read www.EASEnet.dk (he is not affiliated with them).

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CBTp changes the brain’s wiring? Extraordinary claims, ordinary evidence

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Keith Laws and Samei Huda are not impressed by a study on brain connectivity changes following CBT for psychosis, which received a significant amount of press coverage when it was published back in January.

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Antipsychotics for delirium in palliative care: new RCT suggests non-drug alternatives are needed

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Samei Huda highlights a recent RCT of antipsychotics (risperidone and haloperidol) versus placebo for symptoms of delirium in palliative care, which suggests we need non-drug alternatives for this group of patients.

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In praise of little: sponsorship bias in depression research

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Samei Huda welcomes a new meta-analysis of sponsorship bias in the comparative efficacy of psychotherapy and pharmacotherapy for adult depression.

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Schizophrenia, antipsychotics and quality of life: measuring the important things

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Samei Huda mulls over a recent RCT on the effects of older and newer antipsychotics on quality of life in schizophrenia. The study finds a different result to the 10-year old CUTLASS trial; namely that second generation antipsychotics may be superior to first generation antipsychotics in terms of improving quality of life for people with schizophrenia.

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Schizophrenia and urban deprivation: When the facts change, I change my mind. What do you do?

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Samei Huda reviews a recent study of schizophrenia and subsequent urban deprivation, which revisits the social drift hypothesis.

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Prognosis of brief psychotic episodes

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Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.

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The harms of psychotherapy: are BME and LGBT communities more at risk?

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Keith Laws and Samei Huda mull over a recent national survey looking at patients experiences of the harms of psychotherapy. The study reports that both black and minority ethnic people and lesbian, gay and bisexual people reported higher rates of long-lasting negative effects of psychotherapy.

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Antidepressants: benefits and harms in children and adults

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Samei Huda discusses the findings of a recent review into suicidality and aggression during antidepressant treatment. The systematic review and meta-analyses were based on clinical study reports and included some important adverse effects of antidepressants in children and young people.

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Microglial activity in psychosis and schizophrenia

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Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.

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Rise of the machine learning algorithm: the future of diagnosing schizophrenia?

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Samei Huda reviews a meta-analysis of multivariate pattern recognition studies, which aims to detect neuroimaging biomarkers for schizophrenia.

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