Approach Bias Modification didn’t significantly beat standard smoking cessation care, but this may say more about the trial’s power than the intervention itself.
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A systematic review and Delphi study creates a new consensus statement on the meaning and measurement of relapse in schizophrenia, but until voices of lived experience are more fully engaged, there remains some way to go in reaching a valid consensus.
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This network meta-analysis of 76 trials found that slow tapering (over 4 weeks) combined with psychological support was most effective for preventing relapse when stopping antidepressants. Abrupt discontinuation and fast tapering substantially increased relapse risk and should be avoided.
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Laura Naysmith summarises a study of menopausal hormone therapy (also known as HRT), which suggests the treatment is linked with reduce the risk of psychosis relapse in menopausal women.
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Roxanne Keynejad summarises the ESMI-II study on community perinatal mental health teams and mental health, obstetric and neonatal outcomes in pregnant women.
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Andrea Cipriani is back, this time writing with Rosario Aronica to summarise an individual patient data meta-analysis on the use of psychological interventions for preventing relapse in depression.
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Samei Huda summarises a new network meta-analysis in the Lancet Psychiatry on the efficacy and effectiveness of antipsychotics for schizophrenia in research settings, such as randomised controlled trials, versus real-world and clinical settings.
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Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic dosing is best for relapse prevention.
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Raphael Rifkin-Zybutz and Sameer Jauhar summarise the recently published ANTLER trial, which explores whether antidepressant maintenance can reduce the risk of relapse in depression.
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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.
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