Changing sleep patterns linked to cognitive decline and dementia

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Two large cohorts (one UK, one Chinese) found shifting from optimal to non-optimal sleep or stopping napping linked to higher dementia risk. But reverse causation limits certainty about prevention.

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Dirty air, ageing brains: How midlife pollution exposure may accelerate cognitive decline

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Could years of commuting through city smog be leaving lasting marks on our brains? A major UK birth cohort study suggests that midlife exposure to nitrogen dioxide and other pollutants may lead to smaller hippocampal volumes and slower cognitive processing in later life, even after accounting for social and educational factors.

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What’s the matter? The role of white matter microstructure in depression-related cognitive decline

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Fionnuala Rogers discusses a study on the role of white matter microstructure in depression-related cognitive dysfunction, which highlights the importance of viewing major depressive disorder not only as a mood disorder, but as a condition with significant neurocognitive implications.

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Can hearing interventions slow down cognitive decline?

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In this blog, Daisy Long and the elf apprentices that took part in the woodland workshop undertook a group critical analysis on Lin, F.R., Pike, J.R., Albert. M.S., Arnold, M., Burgard, S., Chisolm, T. & others (2023) paper on Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multi-centre, randomized controlled trial.

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New evidence on treatments for symptoms of depression in dementia

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Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.

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Too much TV is associated with decline in verbal memory

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Sarah Gregory summarises findings from a large dataset analysis which explores the relationship between watching television and later cognitive decline.

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Cognitive functioning in psychosis: is neuropsychological decline continuous, generalised, and specific to schizophrenia?

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Emmeline Lagunes Cordoba and Derek Tracy explore a case control study that looks at cognitive change in people with schizophrenia and other psychoses in the decade following the first episode.

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Can museums help prevent dementia?

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Dafni Katsampa and Derek Tracy get all cultured and summarise a retrospective cohort study of museum attendance and dementia incidence, which suggests that cultural engagement may help protect us from cognitive decline.

The research is led by Daisy Fancourt who heads up the new MARCH Network which is launching later this month.

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Dementia in Down syndrome: Are we ready for a clinical trial?

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Leen Vereenooghe summarises the TOP-COG study (Towards Onset Prevention of COGnitive decline in adults with Down syndrome). This pilot RCT highlights the need to educate people with learning disabilities and their carers about the importance of research participation.

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What factors can ameliorate cognitive ageing?

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Raluca Lucacel summarises a systematic review of individually modifiable risk factors to ameliorate cognitive ageing. The study included Mediterranean diet, Tai Chi, Soy isoflavones, B Vitamins and Vitamin D.

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