Should people with schizophrenia be offered depot antipsychotics as first line treatment?

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Murtada Alsaif reports on a new nationwide Swedish cohort study that explores the real-world effectiveness of oral and depot antipsychotics for people with schizophrenia.

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Severe mental illness in offspring may not be linked to smoking during pregnancy

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Andrew Jones considers a recent cohort study that looks into the associations between maternal smoking during pregnancy and severe mental illness in offspring.

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“Won’t you be my neighbour?” Psychosis and violent reoffending: does where you live matter?

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Derek Tracy and Krisna Patel consider neighbourhood influences on violent reoffending risk in released prisoners diagnosed with psychotic disorders.

The blog also features a half hour audio podcast with the lead researcher Amir Sariaslan, the blogger Derek Tracy and Chief Elf André Tomlin.

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OCD risk may increase following perinatal complications

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Alan Underwood summarises a population based cohort study of 2.4 million Swedish children, which highlights links between perinatal risk factors such as smoking during pregnancy, and later development of obsessive compulsive disorder.

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Childhood traumatic brain injuries predict risk of poor long-term outcomes

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Eleanor Kennedy reports on a nationwide Swedish cohort study, which finds that traumatic brain injury consistently predicted later risk of premature mortality, psychiatric inpatient admission, psychiatric outpatient visits, disability pension, welfare recipiency and low educational attainment.

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Alcohol use disorder and increased mortality

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Matt Field summarises a recent Swedish longitudinal cohort study of alcohol use disorder and mortality across the lifespan. This study quantifies the environmental and genetic risk factors that contribute to increased mortality in people with alcohol use disorder.

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Schizophrenia and urban deprivation: When the facts change, I change my mind. What do you do?

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Samei Huda reviews a recent study of schizophrenia and subsequent urban deprivation, which revisits the social drift hypothesis.

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Increased vulnerability of migrants: non-affective psychosis in Sweden

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Mina Fazel considers the findings of a new Swedish cohort study, which looks at the risk of schizophrenia and other non-affective psychoses in refugee migrants and non-refugee migrants from across three continents.

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No link between SSRI use and violent crime in over 25s

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Sarah McDonald considers the implications of a recent cohort study of SSRI use and violent crime, which suffered from the usual headline grabbing media coverage, so typical of research about young people, violence, crime, drugs and mental health.

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