We know how to reduce premature deaths from co-morbid mental health and substance use problems, so why aren’t we doing anything about it?

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Ian Hamilton looks at a Swedish 42-year follow-up study, which looks at the impact that psychiatric comorbidity can have on premature death in a cohort of patients with substance use disorders.

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Risk factors for suicide in people with bipolar disorder

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Dafni Katsampa explores a recent prospective cohort study of risk factors for suicide in bipolar disorder, which finds significant variation in risk factors in men and women.

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Does self-harm in young people increase the risk of subsequent suicide?

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Pooky Knightsmith picks apart a recent Swedish cohort study, which found that all youths presenting to a clinical setting with self-harm were at an elevated future risk of suicide.

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Should people with schizophrenia be offered depot antipsychotics as first line treatment?

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Murtada Alsaif reports on a new nationwide Swedish cohort study that explores the real-world effectiveness of oral and depot antipsychotics for people with schizophrenia.

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Severe mental illness in offspring may not be linked to smoking during pregnancy

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Andrew Jones considers a recent cohort study that looks into the associations between maternal smoking during pregnancy and severe mental illness in offspring.

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“Won’t you be my neighbour?” Psychosis and violent reoffending: does where you live matter?

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Derek Tracy and Krisna Patel consider neighbourhood influences on violent reoffending risk in released prisoners diagnosed with psychotic disorders.

The blog also features a half hour audio podcast with the lead researcher Amir Sariaslan, the blogger Derek Tracy and Chief Elf André Tomlin.

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OCD risk may increase following perinatal complications

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Alan Underwood summarises a population based cohort study of 2.4 million Swedish children, which highlights links between perinatal risk factors such as smoking during pregnancy, and later development of obsessive compulsive disorder.

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Childhood traumatic brain injuries predict risk of poor long-term outcomes

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Eleanor Kennedy reports on a nationwide Swedish cohort study, which finds that traumatic brain injury consistently predicted later risk of premature mortality, psychiatric inpatient admission, psychiatric outpatient visits, disability pension, welfare recipiency and low educational attainment.

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Alcohol use disorder and increased mortality

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Matt Field summarises a recent Swedish longitudinal cohort study of alcohol use disorder and mortality across the lifespan. This study quantifies the environmental and genetic risk factors that contribute to increased mortality in people with alcohol use disorder.

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