schizophrenia

Schizophrenia is a long-term mental health condition that causes a range of different psychological symptoms. These include: hallucinations (hearing or seeing things that do not exist), delusions (unusual beliefs that are not based on reality and often contradict the evidence), muddled thoughts based on the hallucinations or delusions, and changes in behaviour. Doctors describe schizophrenia as a psychotic illness. This means that sometimes a person may not be able to distinguish their own thoughts and ideas from reality.

Our schizophrenia Blogs

Group psychotherapies for schizophrenia

5162224869_52c70e9861_o

Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.

[read the full story...]

No sexual health history please, we’re British!

67865829_18e7655583_b

Kirsten Lawson presents the results of a systematic review of observational cross-sectional studies, which looks at the worldwide prevalence of HIV, hepatitis B and hepatitis C in people with severe mental illness.

[read the full story...]

Lithium for schizophrenia: Cochrane find lack of evidence to support its use

8407060410_e06b0d3e09_k

Raphael Underwood presents a new Cochrane review of lithium for schizophrenia, which assesses the use of lithium as a monotherapy and also in combination with antipsychotics.

[read the full story...]

Microglial activity in psychosis and schizophrenia

Screen Shot 2016-01-12 at 17.15.42

Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.

[read the full story...]

Biological pathways, antipsychotics and schizophrenia

1622916980_ba3ea68e3e_b

Murtada Alsaif summarises a small cohort study that uses shotgun mass spectrometry proteomic profiling to unravel the molecular pathways involved with antipsychotic response in people with schizophrenia.

[read the full story...]

Does QOF reduce hospitalisation for people with severe mental illness?

6324322996_fe28cf8218_b

Andres Fonseca appraises a regression analysis looking at the quality and outcomes framework (QOF) and the impact it has on psychiatric admissions in people with severe mental illness.

[read the full story...]

Rise of the machine learning algorithm: the future of diagnosing schizophrenia?

7232530118_300b9ed694_b

Samei Huda reviews a meta-analysis of multivariate pattern recognition studies, which aims to detect neuroimaging biomarkers for schizophrenia.

[read the full story...]

CBT for insomnia in people with active psychotic symptoms

9383490781_e6ba0bba82_k

Sarah McDonald appraises the Better Sleep Trial (BEST), a pilot RCT which shows that CBT may be a promising treatment for insomnia in people with active psychotic symptoms.

[read the full story...]

Integrated treatment for first episode psychosis: media hype versus reality

7163227255_dafb74ab94_b

Alex Langford reflects on the media hype surrounding a new RCT of the NAVIGATE intervention; a comprehensive, multidisciplinary, team-based treatment approach for first episode psychosis.

[read the full story...]

Can early improvement be used to predict later response to antipsychotics in schizophrenia?

The increased risk of mood and anxiety problems found in people taking varenicline with pre-existing mental health conditions, needs to be investigated further.

Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.

[read the full story...]