schizophrenia

Schizophrenia is a long-term mental health condition that causes a range of different psychological symptoms. These include: hallucinations (hearing or seeing things that do not exist), delusions (unusual beliefs that are not based on reality and often contradict the evidence), muddled thoughts based on the hallucinations or delusions, and changes in behaviour. Doctors describe schizophrenia as a psychotic illness. This means that sometimes a person may not be able to distinguish their own thoughts and ideas from reality.

Our schizophrenia Blogs

Does tobacco use cause psychosis?

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Marcus Munafo appraises a recent systematic review and meta-analysis of prospective, case-control and cross-sectional studies, which finds that daily tobacco use is associated with an increased risk of psychosis and an earlier age at onset of psychotic illness.

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Mood Matters: mood instability is common and associated with poor outcomes

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Farhana Mann summarises an observational study of mood instability in people with mental illness, which explores its relationship with days spent in hospital, frequency of admissions, the likelihood of being sectioned and the chance of being prescribed antipsychotics and mood stabilisers.

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Joining the dots: mental and physical health

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Lia Ali and colleagues from the IMPARTS project present the findings of their group discussions about a recent review of mortality in mental disorders. Along the way she discusses the staff training they carried out and the tweet chat they ran to consider the implications of this research, both to individuals and on the global burden of disease.

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Switching antipsychotics in schizophrenia: the OPTiMiSE RCT

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Tracey Roberts summarises a recent paper that reviews the existing literature concerned with switching antipsychotics in patients with schizophrenia, and goes on to present the ongoing OPTiMiSE RCT in this field, which is due to be published in 2016.

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What psychosocial factors promote and challenge mental health recovery?

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In this blog, Sarah Carr examines a systematic review into the psychosocial factors that help and hinder mental health recovery and discusses implications for policy.

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Smoking cessation for people with severe mental illness

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Sally Adams appraises and summarises the SCIMITAR pilot RCT, which investigates smoking cessation for people with severe mental ill health. The paper presents a highly promising bespoke intervention for smokers with bipolar disorder, psychosis or schizophrenia.

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Smoking and risk of schizophrenia: new study finds a dose-response relationship

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Marcus Munafò looks at the mounting evidence about smoking and risk of schizophrenia, including a new case-control study that provides clear evidence of a prospective association between cigarette smoking and a subsequent diagnosis of schizophrenia.

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Quetiapine for schizophrenia: more transparency needed in clinical trial reporting

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Andrew Shepherd reports on a recent systematic review, meta-analysis and reappraisal of Quetiapine for schizophrenia, which concludes that Quetiapine IR has a small beneficial effect on psychotic symptoms, but also leads to weight gain and sedation.

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CBTp and medication in the treatment of psychosis: summarising the best evidence

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Clive Adams presents a summary of the latest evidence for CBTp and medication in the treatment of psychosis. This blog was published alongside Clive’s talk at the Understanding Psychosis and Schizophrenia conference in Bath on 11 June 2015

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Biological markers for treatment response in first episode psychosis

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Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.

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