Adding antidepressants to antipsychotics in schizophrenia: do they work, for what, and are they safe?

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Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.

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ITI-007 for schizophrenia

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Murtada Alsaif summarises a recent 4-week long phase II randomised controlled trial of ITI-007 for the treatment of schizophrenia, which contains some positive results for this novel intervention.

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Group body psychotherapy for negative symptoms of schizophrenia

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Raphael Underwood reports on the findings of a recent RCT of group body psychotherapy for negative symptoms of schizophrenia, which finds that body psychotherapy did not have a clinically beneficial effect on reducing emotional withdrawal or improving social functioning.

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Transcranial magnetic stimulation for schizophrenia

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Joanne Wallace considers the findings of a new Cochrane systematic review on Transcranial Magnetic Stimulation (TMS) for schizophrenia.

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Diagnostic test accuracy of first rank symptoms for schizophrenia

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Raphael Underwood summarises a recently updated Cochrane systematic review, which aimed to systematically evaluate the accuracy of first rank symptoms for diagnosing schizophrenia.

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Engaging inpatients with mental health rehabilitation activities

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Elly O’Brien reports on a recent RCT of a staff training intervention for inpatients in mental health rehabilitation, which is designed to increase patients’ engagement in activities.

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Exercise for severe mental illness: new review finds few benefits

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This new systematic review concludes that exercise programmes can lead to an improvement in exercise activity, but have no significant effect on mental health symptoms or body weight in people with severe mental illness.

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#MindfulnessMonday – Mindfulness moderately effective for reducing symptoms of psychosis, though controlled studies less convincing

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Last week, Elly O’Brien blogged about mindfulness-based cognitive therapy (MBCT) for various physical and psychological disorders. Today, another paper from the same authors, looking at the more broadly defined ‘mindfulness interventions’ for psychosis. Elly talked about the use of mindfulness to escape the “emotional quicksand” of negative thoughts, and the authors here again focus on [read the full story…]