Results: 3057

For: Populations and settings

Mouth and throat cancer: evidence for best surgical approaches uncertain

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.

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Routine scale and polish for periodontal health

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Two UK primary care-based trials were included in this Cochrane review update of routine scale and polish. They provide high certainty evidence of litte or no difference between 6- & 12-monthly scale and polish for adult regular attenders without severe periodontitis.

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Medication for ADHD: what works for adults, adolescents and children

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Dean Connolly is impressed by a recent systematic review and network meta-analysis, which compares the efficacy and tolerability of medication for ADHD in children, young people and adults.

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Sedation for children undergoing dental treatment

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This Cochrane review update of the efficacy and relative efficacy of conscious sedation agents and dosages for behaviour management in paediatric dentistry includes 50RCTs providing some moderate-certainty evidence that oral midazolam is an effective sedative agent for children undergoing dental treatment.

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Genetic predictors of depression trajectories in adolescence

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Megan Skelton explores a study that uses polygenic scores in the context of longitudinal developmental data, to characterise developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression.

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Parents and volunteers’ experiences of family support

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Jo Moriarty’s blog looks at parents and volunteers’ experiences of Home-Start, a family support programme, via the theoretical framework of liminality.

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Decision-making capacity of inpatients with schizophrenia: don’t assume people are incapable

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Mental Health Masters Students from UCL summarise a recent cross-sectional study on the association of decision-making capacity for treatment and research in inpatients with schizophrenia and related psychoses.

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Vibrational devices: Do they accelerate orthodontic tooth movement?

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Only 5 small low quality RCTs were identified for this review of the ability of vibrational devices to increase the rate of orthodontic tooth movement. More well conducted RCTs are needed.

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Youth suicide prevention research needs a shake-up: lives depend on it

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Pooky Knightsmith appraises a systematic review and meta-analysis entitled: “What Works in Youth Suicide Prevention?”. She is disappointed that the review does not answer the question it sets, but sees this as a call to action for better quality research to help save lives.

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BlueIce app for managing self-harm: what do young people think?

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Bethan Davies shares her thoughts on a qualitative study of service users’ experience about the acceptability, use and safety of the BlueIce app for young people who self-harm.

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