This review of a link between past dental visits/check-ups and the incidence cancers of head and neck includes 38 studies the majority of which are case-controlled studies. The findings suggest that those are irregular of never attenders are more likely to have head and neck cancer.
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12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.
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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .
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This Cochrane review of drugs for the prevention of radiation-induced salivary gland dysfunction included 39 studies, while a range of agents was tested the evidence found is not sufficient to highlight much promise in terms of effective preventative treatments.
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Mark Steven Howe considers this review of extra-oral implant retention. 12 mainly retrospective studies were included providing limited data from which to drawn conclusions regarding the best retention system.
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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.
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This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.
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9 case-controlled studies were included in this review of the effect of marijuana use on head and neck cancer. The findings suggest no association marijuana use and head and neck cancer but other reviews suggest that this may differ by tumour site
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This review of smoking cessation for patients with head and neck cancer included 8 studies ( 3 RCTs) and suggests that those receiving counseling had a 26% higher quit rate than with controls
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This study from the INHANCE collaboration pooled data from 12 case-controlled studies. Long-term use (35 yrs) of mouthwash was associated with an increase risk OR=1.15 (95%CI; 1.01 to 1.30) of head and neck cancer but with regular (>2 x daily), long-term (>35 years) use OR = 1.75 (95%CI; 1.25 to 2.48).
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