Metastasis to the oral and maxillofacial region

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This review of metastasis to the oral and maxillofacial region included 217 studies (190 case reports,24 case series ). Metastasis were uncommon, but identified from 29 primary sites, the most common sites being lung the lungs (20.97%), breast (12.06%) and kidney (11.78%).

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Osteoradionecrosis and denture use in head and neck cancer patients

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This review assessing the evidence of the impact of replacing missing teeth with dentures on the development of osteoradionecrosis in patients who have radiotherapy for head and neck cancer only identified 3 case-controlled studies of very low quality.

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Third molars: Which local anaesthetic is most suitable for inferior alveolar nerve blocks?

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This review comparing the efficacy and safety of currently available local anaesthetics for lower third molar extraction included 24 RCTs. The findings suggest that 4% articaine was the most effective and lidocaine the safest.

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Third molars: Which surgical technique for removal?

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This Cochrane review upate compares the relative benefits and risks of different techniques for surgical removal of mandibular wisdom teeth. While the review includes 25 new trials the quality of the studies was variable with many having biases that could have influenced the findings so no meaningful conclusions could be drawn.

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MRONJ: Medication-related osteonecrosis of the jaw management strategies

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15 systematic reviews were included in this review of teh treament and management of medication-related osteonecrosis of the jaw (MRONJ). The reviews only identified weak evidence to support treatment protocols for MRONJ so high quality well reported RCTs are needed.

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Elective neck dissection versus observation for T1-2 oral squamous cell carcinoma

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Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder being retrospective studies.

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Third molars: Remove or retain asymptomatic disease-free impacted teeth?

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This Cochrane review of the effects of removal compared with retention (conservative management) of asymptomatic disease-free impacted wisdom teeth updates the 2016 version. No new studies were identified so the conclusions are unchanged.

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Third molars: Envelope or triangular flap for mandibular third molar surgery?

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This review comparing the effects of envelope and triangular flaps for mandibular third molar surgery included 20 RCTs involving 770 patients. A majority of the studies were of cross-over design with the findings suggesting no differences in teh outcomes between the two flap designs.

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Third molars: Factors associated with surgical difficulty

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This review of variables associated with surgical difficulty in the extraction of third molars included 16 prospective cohort studies suggesting a number of variable that may be associated with surgical difficulty.

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Elective neck dissection for early stage oral cancer?

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This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END.

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