This Cochrane review update of dthe iagnostic test accuracy of conventional oral examination, vital rinsing, light-based detection, mouth self-examination, remote screening, and biomarkers, used singly or in combination, for the early detection of OPMD or OSCC in apparently healthy adults included 18 studies.
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This review assessing the effectiveness of intraoral stents in reducing toxicities in oral cavity induced by radiotherapy in head and neck region included 7 small studies. While the analysis suggests a beneficial effect from the use of intraoral stents the included studies only provide verylow certainty evidence so further high-quality RCTs are needed.
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This review of the evidence on the malignant transformation of oral proliferative verrucous leukoplakia included 17 mainly retrospective observational studies. The overall estimate for malignant transformation was 43.87% (95% CI; 31.93 to 56.13) but only 4 studies were at low risk of bias.
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This review of the links between the habit of betel quid and areca nut (BQ-AN) chewing and the prognosis of oral cancer included 11 observational studies. The findings suggest that lower 5-year survival is seen in those with a BQ-AN chewing habit.
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This review comparing primary care doctors and dentists in the referral of oral cancer included 22 mainly retrospective studies. Doctors refered sliightly more than dentists, typically 50% compared with 40% respectively.
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Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder being retrospective studies.
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This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END.
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This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.
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This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.
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This review of the association between coffee intake and the risk of oral cancer includes 19 studies and suggestes that higher intak may be linked with a reduced risk of oral cancer.
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