Rajpal Tattar take a look at this review of Raman scattering-based diagnostic systems in oral cavity and oropharyngeal cancer diagnosis.
[read the full story...]Raman spectroscopy in oral cavity and oropharyngeal cancer
No Responses »
Early detection of oral cancer and oral potentially malignant disorders
This Cochrane review update of the diagnostic test accuracy of conventional oral examination, vital rinsing, light-based detection, mouth self-examination, remote screening, and biomarkers, used singly or in combination, for the early detection of OPMD or OSCC in apparently healthy adults included 18 studies.
[read the full story...]Intraoral stents to reduce oral toxicity of radiotherapy
This review assessing the effectiveness of intraoral stents in reducing toxicities in oral cavity induced by radiotherapy in head and neck region included 7 small studies. While the analysis suggests a beneficial effect from the use of intraoral stents the included studies only provide verylow certainty evidence so further high-quality RCTs are needed.
[read the full story...]Oral proliferative verrucous leukoplakia and the rate of malignant transformation
This review of the evidence on the malignant transformation of oral proliferative verrucous leukoplakia included 17 mainly retrospective observational studies. The overall estimate for malignant transformation was 43.87% (95% CI; 31.93 to 56.13) but only 4 studies were at low risk of bias.
[read the full story...]Betel quid and areca nut chewing and oral cancer prognosis
This review of the links between the habit of betel quid and areca nut (BQ-AN) chewing and the prognosis of oral cancer included 11 observational studies. The findings suggest that lower 5-year survival is seen in those with a BQ-AN chewing habit.
[read the full story...]Oral Cancer – Referral by primary care doctors and dentists
This review comparing primary care doctors and dentists in the referral of oral cancer included 22 mainly retrospective studies. Doctors refered sliightly more than dentists, typically 50% compared with 40% respectively.
[read the full story...]Elective neck dissection versus observation for T1-2 oral squamous cell carcinoma
Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder being retrospective studies.
[read the full story...]Elective neck dissection for early stage oral cancer?
This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END.
[read the full story...]Osteoradionecrosis of the jaws: Prevention in adult patients with head and neck cancer
This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.
[read the full story...]Toombak: A risk factor for oral leukoplakia and cancer
This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.
[read the full story...]