Intraoral stents to reduce oral toxicity of radiotherapy

Varian TruBeam Linear Accelerator, Rathiotherapy

This review assessing the effectiveness of intraoral stents in reducing toxicities in oral cavity induced by radiotherapy in head and neck region included 7 small studies. While the analysis suggests a beneficial effect from the use of intraoral stents the included studies only provide verylow certainty evidence so further high-quality RCTs are needed.

[read the full story...]

Oral proliferative verrucous leukoplakia and the rate of malignant transformation

Leukoplakia , Verrucous

This review of the evidence on the malignant transformation of oral proliferative verrucous leukoplakia included 17 mainly retrospective observational studies. The overall estimate for malignant transformation was 43.87% (95% CI; 31.93 to 56.13) but only 4 studies were at low risk of bias.

[read the full story...]

Betel quid and areca nut chewing and oral cancer prognosis

shutterstock_32414035 - Betel leaf

This review of the links between the habit of betel quid and areca nut (BQ-AN) chewing and the prognosis of oral cancer included 11 observational studies. The findings suggest that lower 5-year survival is seen in those with a BQ-AN chewing habit.

[read the full story...]

Oral Cancer – Referral by primary care doctors and dentists

jonathan-borba-iWkA_RzRLuY-unsplash

This review comparing primary care doctors and dentists in the referral of oral cancer included 22 mainly retrospective studies. Doctors refered sliightly more than dentists, typically 50% compared with 40% respectively.

[read the full story...]

Elective neck dissection versus observation for T1-2 oral squamous cell carcinoma

Severe_dysplasia

Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder being retrospective studies.

[read the full story...]

Elective neck dissection for early stage oral cancer?

leukoplakia

This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END.

[read the full story...]

Osteoradionecrosis of the jaws: Prevention in adult patients with head and neck cancer

radiotherapy

This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.

[read the full story...]

Toombak: A risk factor for oral leukoplakia and cancer

29 September 2013. El Fasher: A trader shows a tray with tombac (chewing tobacco) at the market in El Fasher, North Darfur. Tombac is one of North Darfur’s major cash crops. The traditional markets for tombac include South Sudan, Blue Nile and South Kordofan states. Farmers assure four million people in Darfur are dependent on the cultivation and sale of tobacco. They claim that tobacco had been produced in the region since 1850.  Originally, the production of tombac started in Tombouctou (Mali) and later it was imported to Egypt and Darfur.  Photo by Albert González Farran, UNAMID

This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.

[read the full story...]

Mouth and throat cancer: evidence for best surgical approaches uncertain

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.

[read the full story...]