This review of predictors of tooth loss in patients with periodontitis undergoing treatment and receiving supportive care included 20 studies. Findings suggest older, non‐compliant patients, smokers, diabetics, those with IL‐1‐polymorphism, and teeth with bone loss, high probing pocket depths, mobility, as well as molars, especially with furcation involvement, are at higher risk of tooth loss.
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This review of the efficacy of aloe vera mouthrinse on plaque and gingival inflammation includes 6 RCTS providing very low quality evidence that aloe vera mouthwash is comparable to chlorhexidine in reducing gingival inflammation.
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Two UK primary care-based trials were included in this Cochrane review update of routine scale and polish. They provide high certainty evidence of litte or no difference between 6- & 12-monthly scale and polish for adult regular attenders without severe periodontitis.
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38 RCTs were included in this Cochrane review of the effects of autologous platelet concentrates (APC) used as an adjunct to periodontal surgery. Very low quality evidence was found for two approaches involving open flap debridement.
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91 diabetic patients were randomised to non-surgical scaling and root planing and amoxicillin or control. While periodontal status significantly improved at 3 months there was no no significant effects on
glycaemic control.
This Cochrane review of the efficacy of different root coverage procedures for gingival recession included 48 RCTs describing a range of procedures. Most procedures led to a reduction in gingival recession.
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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.
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This review of metformin as an adjunct to scaling and root planing for chronic periodontitis included 5 RCTs that were of limited quality and mainly from one research group. The findings suggest benefit.
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This review of the adjunctive effect of statins on mechanical periodontal therapy included 15 studies 12 of which were RCTs. The findings suggest a positive effect on probing pocket depth, clinical attachment level, and intrabony defects but the overall quality of evidence is considered to be low.
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This review of the association of Vitamin D and periodontal disease identified 27 mainly observational studies providing little data to support or refute the association
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