This review evaluating the efficacy of subgingival instruments for the treatment of periodontitis included 19 RCTs. The findings show that mechanical subgingival instrumentation is efficacious in the nonsurgical treatment of periodontitis, irrespective of type of instrument or mode of delivery.
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This review of the evidence for the relationship between non-surgical periodontal therapy (NSPT) and patient-based outcomes included 13 mainly observational studies. While the findings suggest that NSPT improves oral health related quality of life but the quality of the evidence is limited.
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This review of the impact of of non-surgical periodontal treatment (NSPT) on oral health-related quality of life included 12 studies. The findings suggest that NSPT improves oral health-related quality of life in the short-term.
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Two small RCTs at high risk of bias were included in this Cochrane systematic review looking at the effects of periodontal therapy for primary or secondary prevention of CVD in people with chronic periodontitis.
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This review of minimally invasive periodontal surgery for the treatment of intra‐bony defects included 25 studies of which 10 were randomised controlled trials. There is limitied evidence comparing minimal and traditional approach but minimal invasive surgery may produce similar outcomes.
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This review evaluating the potential efficacy of mesenchymal stem cells in periodontal regeneration included 15 small studies of very low quality. Additional high quality RCTs are neeeded to assess effectiveness before clinicial use.
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This review looked at the adjunctive effects of hyaluronic acid (HA) on surgical or non-surgical periodontal treatment. Thirteen RCTs the majority at high risk of bias suggested that the topical application of HA may lead to additional clinical benefits.
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This review of the efficacy of scaling and root planning (SRP) and SRP + adjuvant treatments in improving glycaemic control in patients with type 2 diabetes mellitus and chronic periodontitis included 14 RCTs suggesting some benefit in the short term.
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This review of predictors of tooth loss in patients with periodontitis undergoing treatment and receiving supportive care included 20 studies. Findings suggest older, non‐compliant patients, smokers, diabetics, those with IL‐1‐polymorphism, and teeth with bone loss, high probing pocket depths, mobility, as well as molars, especially with furcation involvement, are at higher risk of tooth loss.
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This review of the efficacy of aloe vera mouthrinse on plaque and gingival inflammation includes 6 RCTS providing very low quality evidence that aloe vera mouthwash is comparable to chlorhexidine in reducing gingival inflammation.
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