This Cochrane review of the efficacy of different root coverage procedures for gingival recession included 48 RCTs describing a range of procedures. Most procedures led to a reduction in gingival recession.
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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.
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This review of metformin as an adjunct to scaling and root planing for chronic periodontitis included 5 RCTs that were of limited quality and mainly from one research group. The findings suggest benefit.
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This review of the adjunctive effect of statins on mechanical periodontal therapy included 15 studies 12 of which were RCTs. The findings suggest a positive effect on probing pocket depth, clinical attachment level, and intrabony defects but the overall quality of evidence is considered to be low.
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This review of the association of Vitamin D and periodontal disease identified 27 mainly observational studies providing little data to support or refute the association
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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.
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7 small RCTs that majority of cross-over design were included in this review of phytotherapy as an adjunct to scaling and root planing for chronic periodontitis. While the findings suggest a benefit these should be viewed with caution until results from larger high quality studies are available.
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This Cochrane review of the effects of supportive periodontal therapy (SPT) in the maintenance of the dentition of adults treated for periodontitis included 4 RCTs providing is insufficient evidence to determine the superiority of different protocols or adjunctive strategies to improve tooth maintenance during SPT.
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This review of adjunctive use of systemic antibiotics in nonsurgical periodontal treatment of diabetics identified 12 small RCTs. No additional benefit was seen with antibiotic use
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This review of motivational interviewing (MI) as an adjunct to periodontal treatment only included 5 papers reporting 4 studies. The review provides limited evidence to suggest that MI might have a positive effect but more higher quality research is needed.
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