This review of the adjunctive effect of statins on mechanical periodontal therapy included 15 studies 12 of which were RCTs. The findings suggest a positive effect on probing pocket depth, clinical attachment level, and intrabony defects but the overall quality of evidence is considered to be low.
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This review of the association of Vitamin D and periodontal disease identified 27 mainly observational studies providing little data to support or refute the association
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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.
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7 small RCTs that majority of cross-over design were included in this review of phytotherapy as an adjunct to scaling and root planing for chronic periodontitis. While the findings suggest a benefit these should be viewed with caution until results from larger high quality studies are available.
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This Cochrane review of the effects of supportive periodontal therapy (SPT) in the maintenance of the dentition of adults treated for periodontitis included 4 RCTs providing is insufficient evidence to determine the superiority of different protocols or adjunctive strategies to improve tooth maintenance during SPT.
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This review of adjunctive use of systemic antibiotics in nonsurgical periodontal treatment of diabetics identified 12 small RCTs. No additional benefit was seen with antibiotic use
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This review of motivational interviewing (MI) as an adjunct to periodontal treatment only included 5 papers reporting 4 studies. The review provides limited evidence to suggest that MI might have a positive effect but more higher quality research is needed.
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15 RCTs were included in this Cochrane review of impact of periodontal treatment on adverse pregnancy outcomes. all the included studies were considered to be at high risk of bias. There was no evidence that periodontal treatment reduces the number of preterm babies.
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35 studies investigating 47 clinical groups were included in this review of the association between dental anxiety and pain during dental treatment. The findings suggest a consistent impact on pain through the entire period of dental treatment.
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This review of intra-pocket anaesthesia for patients having scaling and root planing included 11 trials and demonstrated a benefit over placebo.
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