What’s the relationship between stressful life events and psychosis?

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Kris Deering considers a 2-year prospective observational study published in the Lancet Psychiatry which found strong links between stressful life events and relapse in first-episode psychosis.

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Is persistent anxiety and depression in childhood a one-way road to adverse outcomes in adulthood?

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In her latest blog, Laura Hankey summarises a longitudinal study using ALSPAC data that explored associations between anxiety, depression, and comorbid anxiety/depression in childhood and adverse outcomes in young adulthood.

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Genetic risk for schizophrenia is associated with changes in heart structure and function

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Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

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Mapping the trajectory of psychiatric diagnoses: Danish study finds that mental health diagnoses may change over time

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In her latest blog, Dona Matthews summarises a recent publication in The Lancet Psychiatry, which mapped the psychiatric diagnostic trajectories of 184,949 Danish patients over a 10-year period.

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Psychosis and loneliness: overcoming the practical, social and emotional barriers to better relationships

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Hosana Tagomori and Dafni Katsampa review a qualitative study exploring the experience of loneliness among people diagnosed with psychosis.

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Where I lay my head is home: residential instability and earlier onset of psychosis

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Liana Romaniuk summarises a recent US cross-sectional study which suggests that residential instability (moving home a lot) may lead to disrupted social networks and relationships, predisposing vulnerable youth to greater stress, which can increase their risk of psychosis.

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Virtual reality therapy for psychosis: positive patient experiences and few side effects

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Steven Parkes considers a randomised controlled trial exploring the satisfaction and side effects of gameChange, a virtual reality intervention targeting anxiety in every day situations for patients with psychosis.

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Is trauma a transdiagnostic risk for mental health problems? Recent umbrella meta-analysis suggests yes

Mental health services worldwide operate using discrete categories, but significant symptom overlap between different mental health disorders suggests that transdiagnostic approaches may be plausible.

In her debut blog, Megan Bailey summarises an umbrella review of systematic reviews and meta-analyses on whether psychological trauma can be considered as a transdiagnostic risk factor for mental health disorders.

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Blood-based inflammatory markers in acute vs chronic schizophrenia

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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

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People with severe mental health difficulties are more likely to have poor dental health and dental disorders

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Masuma Pervin Mishu summarises an umbrella review on the prevalence of dental disorders among people with severe mental illness.

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