Optimal antipsychotic dosing in first-episode schizophrenia: how much is too little, too much, or just right?

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Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic dosing is best for relapse prevention.

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Uncertainties about stopping or reducing antipsychotics as shared by families

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Amelia Talbot considers a qualitative study that explores family members’ perspectives on reducing or discontinuing antipsychotic medication.

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Can therapeutic alliance help prevent suicide in people with psychosis?

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Melanie Lafanechere and Dafni Katsampa summarise a study on the therapeutic alliance and suicidal experiences in people with psychosis receiving Cognitive Behavioural Suicide Prevention Therapy.

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An INTREPID journey into the epidemiological landscape of psychosis in the Global South

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Shuichi Suetani and Jon Paul Teo discuss the International Research Program on Psychotic Disorders in Diverse Settings (INTREPID II) study, which investigates the epidemiology of untreated psychoses in 3 diverse settings in the Global South.

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Can social recovery therapy improve social disability in young people?

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In her debut blog, Jude Madani summarises the findings of the PRODIGY trial, which looked at the clinical and cost-effectiveness of social recovery therapy for the prevention and treatment of long-term social disability among young people with emerging severe mental illness.

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Do different groups of people with schizophrenia respond differently to different antipsychotics?

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Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.

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Oral health interventions for people with severe mental illness: what enables and prevents people from accessing them?

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Vishal Aggarwal considers the findings of a recent qualitative study, which looks at the contextual factors, barriers, and facilitators to accessing oral health interventions for people with severe mental illness.

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Severe mental illness and comorbid chronic physical illness: the clock’s ticking

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In her debut blog, Jodie Ferris summarises a recent cohort study on the temporal relationship between severe mental illness diagnosis and chronic physical comorbidity in the UK, which contains important findings for care and future research.

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Early intervention in psychosis: research priorities

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In his debut blog, Kris Deering summarises a paper which looks at the evidence gaps and research priorities for early intervention in psychosis.

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Acceptance and commitment therapy for early psychosis: results from the INTERACT trial

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Silke Vereeken summarises the INTERACT randomised controlled trial, which reports on the efficacy of Acceptance and Commitment Therapy in daily life for people with early psychosis.

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