People with severe mental illness often face years of poor health before diagnosis. A new study uses machine learning and clinical notes to map the early warning networks of symptoms that could help us intervene earlier.
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This big meta-analysis pooled 155 studies from 37 countries and found many more delusional themes than standard assessment tools capture. Clinicians should watch for “non-classical” content, and researchers should widen how we measure delusions.
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Negative core beliefs like “I’m worthless” or “people can’t be trusted” are linked to hallucinations, paranoia, and suicidality. This new systematic review shows how deep-rooted schemas shape psychosis, and what this means for psychological therapies.
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CBT is a cornerstone of mental health care, but how well does it really work across different disorders? This massive new meta-analysis offers some answers and raises new questions.
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People with psychosis face unique risks around suicide, but most treatments aren’t designed with them in mind. This new RCT tested a targeted therapy that tackles those specific challenges. So what did it find?
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Emotional abuse in childhood was linked to a more than 3.5x greater chance of developing psychosis later in life. This comprehensive new meta-analysis explores the role of early trauma, sex differences, and symptom onset timing in psychosis risk.
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Shuichi Suetani and Jon Paul Teo consider a new systematic review, which highlights the significant stigma faced by people with psychosis and their families in Middle Eastern communities, and suggests culturally sensitive ways forward.
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KCL MSc student Geetika Sharma reviews a study that looks at the contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.
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Dr Fabiana Corsi-Zuelli discusses the differences in immune cell counts in patients with schizophrenia compared to controls; highlighting a recent meta-analysis by Dudeck et al. (2025) that reinforces the growing consensus that immune dysfunction plays a role in schizophrenia.
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A group of UCL MSc students reflect on a qualitative review looking at the experience of loneliness among people with psychosis, which makes actionable clinical suggestions to enhance connection and address isolation.
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