Is persistent anxiety and depression in childhood a one-way road to adverse outcomes in adulthood?

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In her latest blog, Laura Hankey summarises a longitudinal study using ALSPAC data that explored associations between anxiety, depression, and comorbid anxiety/depression in childhood and adverse outcomes in young adulthood.

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Patients’ experience of ketamine treatment for depression: the ‘Ketamine and me’ project

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In her debut blog, Harmony Jiang reviews a recent qualitative study exploring patients’ experience and response to ketamine treatment for depression.

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RESPECT! Find out what it means to me(ntal health services)

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Beccy White explores the recently published RESPECT trial – a feasibility RCT which finds that a sexual health promotion intervention was safe and acceptable for people with severe mental illness.

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Cost-effectiveness of CBT for depression: uncertainty remains

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Chris Sampson reviews a recent US study which looks at the cost-effectiveness of CBT versus second-generation antidepressants for the initial treatment of major depressive disorder.

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Persistent and severe postnatal depression predicts adverse outcomes in children

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Sophie Graham and Jennifer Burgess explore the associations between persistent and severe postnatal depression in mothers and mental health and educational outcomes in their offspring.

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CBT and severity of depression

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Joe Hayes summarises a new meta-analysis in the British Journal of Psychiatry that shows how the initial severity of depression does not alter the efficacy of cognitive behavioural therapy.

This is the first in a new series of Mental Elf blogs produced in partnership with the British Journal of Psychiatry.

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Specialist depression service may help people with persistent depression

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Ben Hannigan reports on a recent RCT of the efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression.

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Mindfulness-based cognitive therapy can prevent recurrent depression

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Sarah McDonald reports on a meta-analysis published yesterday, which found that when compared with active treatment, mindfulness-based cognitive therapy resulted in a reduced risk of depressive relapse.

This blog also features a podcast interview with the lead author of the research, Professor Willem Kuyken.

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Antidepressants for depression: new BAP guidance

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Helge Hasselmann summarises the recently published evidence-based guidance on antidepressants for depression published by the British Association for Psychopharmacology.

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ECT for depression in the elderly

Depression and anxiety are quite common in people with dementia and mild cognitive impairment.

Andrew Shepherd reports on a post-hoc analysis of pre-existing trial data, which does little to convince him that ECT is a safe and effective treatment option for older people with severe depression.

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