Susannah Murphy summarises a new Cochrane review and network meta-analysis, which provides the best evidence to date about new generation antidepressants for depression in children and adolescents.
[read the full story...]
This review the efficacy of stabilisation appliances in the management of painful temporomandibular disorders (TMDs) included 24 RCTs. The findings suggest they have an efficacy beyond the placebo effect however the evidence of low to very low certainty.
[read the full story...]
This network meta-analysis of the efficacy of antifungal drugs on oral candidiasis included 31 RCTs of overal low quality suggesting that fluconazole may be the most effective.
[read the full story...]
This review of the effects of different types of lasers on dentine hypersensitivity included 11 RCTs suggesting no significant differences between Er,Cr:YSGG, Nd:YAG, Er:YAG, and GaAlAs lasers both in the immediate term and at 1 month.
[read the full story...]
This network meta-analysis comparing the effect of different desensitising toothpastes on dentine hypersensitivity included 30 RCTs. The findings suggest that toothpastes containing nano-hydroxyapatite or arginine may be the most effective. However additional larger studies are required.
[read the full story...]
Inês Pote summarises a recent meta-analysis of randomised placebo-controlled trials of cognitive behavioural therapy for anxiety and related disorders.
[read the full story...]
This network meta-analysis of oral premedication to improve anaesthetic success of inferior alveolar nerve block in patients with irreversible pulpitis suggest that that oral premedication with dexamethasone, NSAIDs and Tramadol increases the success rate.
[read the full story...]
Students and Teachers from the King’s College London PNoMH Distance Learning MSc summarise a major new meta-analysis that brings together the last 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia.
[read the full story...]
André Tomlin reports on a new network meta-analysis that brings together the best available evidence comparing the efficacy and acceptability of 21 antidepressants for the acute treatment of adults with major depressive disorder.
This groundbreaking review of 522 trials is the largest ever meta-analysis in psychiatry, and finds that antidepressants are more effective than placebo for short-term treatment of acute depression in adults.
[read the full story...]
This review of the effectiveness of silver diamine fluoride (SDF) in arresting caries included 11 studies with 4 contributing to a meta-analysis showing it to be more effective than other active agents and placebo.
[read the full story...]
