Joe Pierre summarises two recently published and widely reported RCTs, which suggest that antipsychotic medication might not offer an advantage over psychotherapy in broadly-defined first episode psychosis.
[read the full story...]
Dolly Sud writes her debut elf blog on a recent retrospective analysis, which compares dose changes of risperidone and aripiprazole with patients’ individual genotype.
[read the full story...]
Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.
[read the full story...]
Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).
[read the full story...]
This review of amoxicillin & metronidazole as an adjunct to non-surgical periodontal treatment included 18 trials . A small benefit was seen with antibiotic use but no clinically meaningful difference between different doses or duration of amoxicillin-plus-metronidazole at 3 months post-treatment.
[read the full story...]
Sarah Knowles appraises a recent study of UK routine practice, which looks at the effect that duration of psychotherapy has on recovery and improvement rates.
[read the full story...]
Andrew Shepherd summarises a meta-analysis, which looks at the dose equivalents of antidepressants by bringing together data from 83 trials of 23 different antidepressants.
[read the full story...]
