Jessica Scaife

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Jessica is a cognitive neuroscientist with a background in human psychopharmacology. She uses behavioural models, neuroimaging, brain stimulation and electrophysiological techniques in experimental medicine paradigms of mood and eating disorders. Jessica is currently working on study in people experiencing low mood, investigating the effects of a 5HT4 agonist, which is a novel antidepressant target. She also has recently completed a longitudinal deep brain stimulation study in anorexia nervosa with MEG. Jessica is a qualified secondary school science teacher with a passionate for Public Engagement and Open Science. Her interests include Cognitive Neuroscience, Experimental Medicine, Eating Disorders, Open Science, Psychiatry, Clinical Trials, Meta-analyses, Neuroimaging, Mood disorders, Brain stimulation, Addiction, Education.


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Psychotherapy and antidepressant tapering can help people at risk of depression relapse, but more evidence needed before we can provide personalised treatment


Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.

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