Optimal antipsychotic dosing in first-episode schizophrenia: how much is too little, too much, or just right?

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Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic dosing is best for relapse prevention.

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Alcohol consumption increased oral cancer risk

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This new review investigated the effect of alcohol on 23 cancer types. They included 572 case-control and cohort studies and using meta-analysis and a dose–response meta-regression model found relative risks for heavy drinkers compared with nondrinkers and occasional drinkers were 5.13 for oral and pharyngeal cancer, 4.95 for oesophageal squamous cell carcinoma, 1.44 for colorectal, 2.65 for laryngeal and 1.61 for breast cancer.

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