The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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Are circadian rhythms the key to understanding our physical and mental health?

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Amy Ferguson discusses the latest research exploring the role of our circadian rhythms on our health, looking at different variants in the BMAL1 gene.

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Inheriting the traumas of war: examining DNA methylation across three generations of Syrian refugees

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In her debut Mental Elf blog, Demelza Smeeth discusses the latest research on the inheritance of trauma across three generations of Syrian refugees; summarising a paper that looks into the epigenetic signatures of intergenerational exposure.

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Genetic risk for Tourette Syndrome and related conditions

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Ed Palmer considers new research on the genetic risk for Tourette Syndrome and it’s relationship to other mental and physical health conditions.

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How do our genes affect our risk of suicidal thoughts and behaviours in childhood?

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A group of UCL masters students consider a JAMA Psychiatry study which looks at the associations between genetic risk for adult suicide attempt and suicidal behaviours in young children in the United States.

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Victimisation and loneliness: who is more likely to become lonely?

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A group of UCL Mental Health MSc students summarise a recent longitudinal twin study of the association between victimisation and loneliness from childhood to young adulthood.

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