What can genetics tell us about the link between cannabis and schizophrenia? #MHQT

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Suzi Gage summarises a recent GWAS of lifetime cannabis use, which reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Interesting new evidence ahead of our Mental Health Question Time #MHQT event in London tomorrow.

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Medical cannabis for mental illness: current use is not supported by research #MHQT

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As we prepare for our Cannabis #MHQT event on Wed 26 Sep, Luke Sheridan Rains dissects a narrative review that asks: Is cannabis treatment for anxiety, mood, and related disorders ready for prime time?

His answer is that current evidence does not support the use of medical cannabis for mental illnesses such as anxiety or depression.

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Is Cannabidiol (CBD) an effective antipsychotic?

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Luke Sheridan Rains publishes his debut blog on a recent multicentre RCT of Cannabidiol (CBD) as an adjunctive therapy for people with schizophrenia, which suggests that CBD had a beneficial, but modest impact on positive psychotic symptoms and severity of illness when used alongside existing antipsychotics.

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Joint risks? Tobacco and cannabis and psychotic symptoms

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James MacCabe appraises a recent study, which looks at the association of combined patterns of tobacco and cannabis use in adolescents who go on to experience psychotic symptoms.

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Adolescent cannabis use increases risk of an adult psychotic diagnosis

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Thomas Richardson looks at a recent prospective cohort study in the British Journal of Psychiatry on adolescent cannabis use, baseline prodromal symptoms and the risk of psychosis.

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What do we know about women, cannabis and psychosis?

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Ian Hamilton and Suzi Gage explain why we know so little about the relationship between cannabis and severe mental illness in women.

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Risk factors and peripheral biomarkers for schizophrenia spectrum disorders

This 'umbrella review' aimed to systematically appraise the meta-analyses of observational studies on risk factors and peripheral biomarkers for schizophrenia spectrum disorders.

Marcus Munafo considers the findings of a systematic review of meta-analyses of observational studies, which looks at risk factors and peripheral biomarkers for psychotic disorders on the schizophrenia spectrum.

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Cannabis use can lead to relapse in psychosis, partially because patients stop taking medication

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Thomas Richardson writes his debut blog about a recent prospective analysis of poor medication adherence and risk of relapse associated with continued cannabis use in patients with first-episode psychosis.

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Does cannabis influence depression?

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Rob Allison and Ian Hamilton summarise a recent retrospective twin cohort study that explores the links between cannabis use and depression, suicidal thoughts and behaviours.

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Cannabis and psychosis: it’s high time for a review

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Joe Barnby considers the findings of a recent meta-analysis of cannabis use and symptoms severity in individuals at ultra-high risk for psychosis.

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