Inferior alveolar nerve block 2% mepivacaine versus 4% articaine – trial

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This well conducted randomised controlled trial assessed inferior alveolar nerve block (IANB) success of 2% mepivacaine and 4% articaine in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation.

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Anaesthetic techniques for mandibular posterior teeth with symptomatic irreversible pulpitis

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This review of the most effective method of anaesthesia for mandibular posterior teeth with symptomatic irreversible pulpitis included 22 RCTs. The findings suggest that buccal infiltraion and inferior alveolar nerve block ,Vazirani-Akinosi nerve block and introsseus injections performed better but the evidence was only of low to very low certainty.

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Articaine local anaesthesia and the risk of hyperaesthesia in third molar surgery

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This review of the risk of hyperaesthesia with articaine compared with other local anaesthetics in lower alveolar nerve block for lower third molar removal included 13 studies.The findings suggest that the use of articaine does not increase the risk of hyperaesthesia.

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Third molar extractions: Which anaesthetic solution for the best pain control?

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This review of the effectiveness of different anaesthetic solutions for pain control immediately after the extraction of lower third molars included 45 studies.13 studies were included in a network meta-analys whch suggested 5% bupivacaine reduces pain in patients during and immediately after the removal of lower third molars.

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Third molars: Which local anaesthetic is most suitable for inferior alveolar nerve blocks?

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This review comparing the efficacy and safety of currently available local anaesthetics for lower third molar extraction included 24 RCTs. The findings suggest that 4% articaine was the most effective and lidocaine the safest.

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Computerised local anaesthesia in paediatric patients

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This review ofwhether local computerised anaesthesia decreases the pain and disruptive behaviour in children when compared to conventional anaesthesia included 20 RCTs and suggested no diference between the two approaches.

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Irreversible pulpitis: What is the most effective local anaesthetic for inferior alveolar nerve block?

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This review of the most effective anaesthetic solutions for inferior alveolar nerve blocks for mandibular teeth with irreversible pulpitis included 11 RCTs. The findings suggest that mepivacaine with epinephrine performed better than lidocaine with epinephrine but the number of trials is limited and the quality of evidence was very low to moderate.

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Inferior alveolar nerve block: mepivacaine-lidocaine no better than lidocaine alone suggests trial

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This well conducted and reported trial found that there was no difference between 3% mepivacaine & 2% lidocaine with 1:100,000 epinephrine and 2 cartridges of 2% lidocaine with 1:100,000 epinephrine in terms of injection pain, onset time, and pulpal anesthetic success for the IAN block.

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