This review comparing plaque accumulation in orthodontic patients undergoing clear aligner (CA) and conventional fixed appliance treatment included 14 studies. The findings suggested less plaque accumulation with CA but all the included studies were at moderate to high risk of bias.
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270 pateints were randomised in this trial to compare high-fluoride toothpaste and high-fluoride mouth rinse for preventing white spot lesions during orthodontic treatment. The findings suggest a benefit for high fluoride toothpaste and fluoride mouth rinse in preventing white spot lesions.
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This review and network meta-analysis of seven treatments for white spot lesions (WSLs) included 36 clinical RCTs published since 2007. The findings suggest that self-assembling peptide P11-4 and resin infiltration had a positive effect on WSLs but the findings should be interpreted cautiously.
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This review evaluating the preventive effect of regular applications of fluoride varnish (FV) on the development of white spot lesions (WSL) during orthodontic treatment included 7 RCTs. Meta-analyses demonstrated a reduction in the risk of WSL with regular FV applications but the certainty of evidence was very low.
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Early detection of oral cancer and mangement of white spot lesions during orthodontic treatment were popular blogs in January , February and March of 2022.
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This overview of systematic reviews of evidence for the prevention of enamel demineralization during fixed appliance orthodontic treatment included 29 reviews. Most of the reviews were considered to have methodological issues with the findings suggesting that professional fluorides, sealants, reminders, and lasers might be useful interventions to prevent enamel demineralization.
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This review of the efficacy of fluoride-free nano-hydroxyapatite agents (nHA) to enhance remineralisation or hamper demineralisation of enamel caries included 10 small studies. 5 studies were in-vivo and 5 in-situ but they were of short duration with 7 being at high risk of bias so provide very low certainty evidence. Additional high quality well reported studies are needed to assess nHA.
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This review of the long-term efficacy of resin infiltration therapy for white sport lesions with regard to aesthetic appearance and long-term stability included 11 studies 9 of which were RCTs. The findings suggest a benefit but the amount of evidence is limited.
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This Cochrane review update evaluates whether topical fluoride reduces the proportion of orthodontic patients with new demineralised lesions (white spot lesions). In included 10 studies finding some low certainty evidence that some topical fluorides reduced white spot lesions.
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This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.
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