Metronidazole for treatment of non-periodontal dental infections

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This review of whether metronidazole used as monotherapy or in addition to a β-lactam antibiotic offers any additional benefit over β-lactam monotherapy in non- periodontal dental infections includes 3 RCTs. The findings suggest that metronidazole does not provide superior clinical results compared to β-lactam antibiotics for the treatment of non-periodontal dental infections. However the evidence is limited and of low quality.

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Apical Periodontitis – Is treatment with modern root canal instrumentation more effective?

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In this blog Thibault Colloc looks at a review of comparing the effectiveness of contemporary root canal instrumentation compared with conventional stainless-steel instruments in terms of clinical and patient-related outcomes. The review includes 9 studies (6 RCTs and 3 retrospective clinical studies) and was one of a series designed to inform guidelines for the European Society of Endodontics.

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How common is root canal treatment?

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This review of prevalence of root filled teeth in the adult population worldwide included 76 observational studies. The findings suggest that 8.2% (95%CI; 7.3% to 9.1%) of teeth has been root filled and that 55.7% (95%CI; 49.6% to 61.8%) of people had at least one tooth root filled.

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Primary root canal treatment success rates

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Thiis review of the outcomes of primary root canal treatment (RoCT) in studies published since 2003 included 42 studies (15 RCTs, 14 prospective cohorts and 13 retrospective studies. While pooled success rates were high the quality of the included studies was limited and the studies were conducted in an academic or private practice environment.

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Endodontic sealers and the outcome of endodontically treated permanent teeth

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This review comparig the outcomes of silicate-based sealers with resin-based sealers in non-surgical root treatments included 12 studies (9 RCTs). The findings suggest no difference between the two sealant types in the short term.

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Which retrograde root filling material?

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This Cochrane review update of different materials used for retrograde root filling in children and adults requiring retrograde filling included 8 RCTs. However the studies are all at high risk of bias so provide insufficient evidence for the benefits of any one material.

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Occlusal reduction and post-endodontic pain

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This review analysing the influence of occlusal reduction on postoperative pain levels after endodontic treatment includes 12 RCTs. The findings suggests no difference was seen in post-treatment pain levels after occlusal reduction.

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Post-operative endodontic symptoms: Are they improved by prophylactic antibiotics?

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This review of the efficacy of prophylactic oral antibiotics in the management of post-operative endodontic symptoms included 10 RCTs. The findings and show that there is no superiority in using adjunctive antibiotics for the prevention of post-operative endodontic symptoms.

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Intracanal cryotherapy in root canal treatment

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This review of the effect of intracanal cryotherapy in reducing postoperative pain after instrumentation or obturation in root canal treatment included 8 RCTs. The findings suggest that suggests that intracanal cryotherapy in the form of cold saline irrigation as the final irrigant significantly reduces pain between 6 and 24 hours after root canal therapy.

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Occlusal reduction: Does it reduce post endodontic pain?

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This review of the effect of occlusal reduction on post-operative pain following root canal treatment included 7 RCTs. While the findings suggest that occlusal reduction may reduce post endodontic pain the quality of the available evidence is very low so teh findings should be viewed cautiously.

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