Anticoagulants and post-operative bleeding following oral surgery

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This review of the post oral surgery bleeding risk for patients on direct oral anticoagulants (DOACs) included 13 observational studies. The findings suggest a three-fold increase in bleeding for those patients on DOACs although the quality of the available evidence is limited.

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Fixed appliance orthodontics: extraction or non-extraction and soft tissue changes

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52 studies were identified for this review of the effect of extraction or non-extraction fixed orthodontic treatment of soft tissue profiles . However they were mainly poor quality retrospective studies providing very low quality evidence suggesting that tooth extractions might be associated with differences in the soft tissue profile compared to non-extraction treatment.

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Bleeding after dental extraction: no evidence from randomised trials

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This update of a 2016 Cochrane Oral Health Group review of interventions for post extraction bleeding was unable to identify any published or ongoing trials assessing interventions. Well conducted and reported randomised controlled trials are needed on this question.

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Third molar extraction – does platelet-rich fibrin improve outcomes?

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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.

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Tooth socket preservation using autologous platelet concentrates

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33 studies were included in this review of the effectiveness of autologous platelet concentrates (APCs) in the preservation of fresh extraction sockets. The studies were mainly small and of less than 6 months duration suggesting a positive effect.

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Chlorhexidine gel and alveolar osteitis

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This review of the effectiveness of chlorhexidine gel for the prevention of alveolar osteitis (AO) included 10 trials published since 2010. The findings suggest a 57% reduction in incidence of AO similar to other reviews of this topic.

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Chlorhexidine gels and rinses reduce dry socket after third molar extraction

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This review of the effectiveness of chlorhexidine for prevention of dry socket after third molar removal includes 18 RCTs. The finding suggest a 47% (95%CI,38-55) reduction in cases following its use.

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Anxiety and pain during dental treatment

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35 studies investigating 47 clinical groups were included in this review of the association between dental anxiety and pain during dental treatment. The findings suggest a consistent impact on pain through the entire period of dental treatment.

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Orthodontic extractions and third molar angulation

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This review of the effect of orthodontic extractions on the angulation of third molars included only 14 retrospective studies. This provides very low quality evidence of any effect

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