Predicting psychiatric hospitalisation using routinely-collected measures

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Psychiatric hospitalisation can save lives, but it also carries major personal and economic costs. Could early warning scores help predict who’s most at risk, allowing for earlier, more targeted support? This new BMJ Mental Health study by Taquet and colleagues explores the potential.

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Mind the age gap: Young adults may benefit less from NHS psychological therapies

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If NHS Talking Therapies work so well, why are recovery rates lower for young adults? Saunders and colleagues analysed data from 1.5 million people to find out, and the results show an urgent need to rethink how we support young people in distress.

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Inside the diagnostic grey zone: using machine learning to separate bipolar and major depression

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High misdiagnosis rates between bipolar and major depressive disorder cause real harm to patients and services. This new neuroimaging study tested whether brain connectivity and machine learning could do a better job of telling the two apart, with interesting but limited results.

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Is it a gut feeling? How the microbiome may shape perinatal mental health in women with higher body weight

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What if perinatal mental health started in the gut? New research from Finland suggests certain bacteria may be associated with depressive and anxiety symptoms during pregnancy and after birth, raising questions about inflammation, causality, and the future of microbiome-based screening and treatment.

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Solastalgia and the mental health impacts of environmental loss

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Climate change is reshaping not just the planet but our emotional lives. Could solastalgia (“solace” (comfort) and “nostalgia” (homesickness)) be a key pathway linking environmental loss to mental distress? This new scoping review of global studies investigates.

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Mindfulness-based cognitive therapy proves cost-effective for hard-to-treat depression

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What happens when talking therapies or antidepressants don’t work? This new RCT tested whether mindfulness-based cognitive therapy (MBCT), delivered via Zoom, could help people with hard-to-treat depression, and whether it’s worth the cost. The results will interest NHS decision-makers.

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Out at work? A systematic review of LGBTQ+ mental health in the workplace

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Depression, anxiety, and suicidality are higher among LGBTQ+ workers, especially in hostile or unsupportive workplaces. But are research and policy keeping up? This new review sets out the case for change.

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Adolescent versus adult depression: Is risk of recurrence the same?

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Is teenage depression more likely to come back later in life? A new population study challenges assumptions and finds similar recurrence risks in both adolescents and adults.

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Ketamine, depression and childhood trauma: new evidence from a community study

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Can ketamine help people with treatment-resistant depression, regardless of childhood trauma history? This new study suggests that trauma load and severity may not influence treatment outcomes.

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