Inside the diagnostic grey zone: using machine learning to separate bipolar and major depression

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High misdiagnosis rates between bipolar and major depressive disorder cause real harm to patients and services. This new neuroimaging study tested whether brain connectivity and machine learning could do a better job of telling the two apart, with interesting but limited results.

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Anti-inflammatory treatments for youth depression: promising but not yet implementable

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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.

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