Local anaesthetics for preventing pain during dental treatment

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123 RCTs were included in this Cochrane review of local anaesthetic agents for preventing pain during dental treatment. 14 types of local anaesthetic were included evidence to support the use of one over another was limited so further research is needed to clarify the effectiveness and safety of one local anaesthetic over another.

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Infraorbital nerve block for postoperative pain following cleft lip repair in children

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This Cochrane review of Infraorbital nerve block for postoperative pain after cleft lip repair includes 8 trials providing low to very low quality evidence that infraorbital nerve block with lignocaine or bupivacaine may reduce postoperative pain more than placebo

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Bupivacaine may reduce post-operative pain in patients having single visit root canal treatment

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Elimination of pain during and after root canal treatment is an important element of patient care and modern endodontic practice.  The aim of this study was to compare the postoperative pain and analgesic use after single-visit root canal treatment of acute irreversible pulpitis with either bupivacaine (a long-acting anaesthetic) or lidocaine. Patients with a first [read the full story…]

Side effects of local anaesthetics

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Local anaesthetic use is widespread in dentistry and while lidocaine has been in use for more than 50 years an increasing number of agents are now available. The aim of this study was to analyze adverse drug reactions (ADRs) associated with local anesthetics (LAs) and to characterize the safety profile of LAs in clinical application. [read the full story…]