Mucositis in adult cancer patients reduced with keratinocyte growth factor

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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .

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Hepatitis C and oral lichen planus

HCV

This review of the association between hepatitis C virus (HCV) and oral lichen planus (OLP) identified 19 case-controlled studies. While a 6-fold increase in risk of HCV infection was noted in OLP patients a majority of the studies took place in areas with high endemic HCV rates and there is some concern regarding publication bias and the quality of the available studies.

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Laser therapy for oral lichen planus

Lichen_planusWickham's

This review comparing low level laser therapy (LLLT) with steroids for the treatment of oral lichen planus only identified 5 studies none of which were at low risk of bias. Further high quality trials are needed to assess the efficacy of LLLT.

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Denture stomatitis: some evidence for nystatin and disinfecting agents

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This review of interventions for the management of denture stomatitis identified 35 RCTs. A majority of the RCTs were at high risk of bias. The findings suggest that nystatin and disinfecting agents have a positive effect but the results should be viewed cautiously because of the quality of the available evidence

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Oral mucositis in cancer patients: no benefit from chlorhexidine mouthwash

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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.

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Parotid gland tumours and mobile phone use?

The study used data from a previous telephone survey, which focused on depression, concussion and brain injury, amongst other things

This review of parotid gland tumours and mobile phone use included 3 case-controlled studies and hints at a possible association. However the limited evidence means that the findings should be viewed very cautiously.

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External root resorption diagnosis: cone-beam computed tomography or periapical radiographs?

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15 in-vitro studies were included in this review of CBCT & periapical radiographs for the diagnosis of external root resorption. It suggests that CBCT performs better however further research is needed the clinical an cost -effectiveness of its use.

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Burning mouth syndrome: insufficient evidence for effectiveness of current treatments

Depression

This update of a 2005 Cochrane review identified 23 RCTs but a limited number at low risk of bias so there is insufficient evidence to support or refute the use of any interventions in managing burning mouth syndrome.

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Oral Mucositis: can honey reduce its severity?

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This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.

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Keratocystic odontogenic tumors: which treatment approach?

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This review of the management of keratocystic odontogenic tumors included 14 mainly retrospective studies ans suggests that initial cystectomy, with or without adjuvant therapy, is associated with the least chance of recurrence.

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