Recurrent aphthous stomatitis and serum zinc levels

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This review of the potential association between zinc levels and occurrence of Recurrent aphthous stomatitis (RAS) included 19 case-controlled studies. The findings show a sigificant association between low zinc levels and RAS.

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Betel quid and areca nut chewing and oral cancer prognosis

shutterstock_32414035 - Betel leaf

This review of the links between the habit of betel quid and areca nut (BQ-AN) chewing and the prognosis of oral cancer included 11 observational studies. The findings suggest that lower 5-year survival is seen in those with a BQ-AN chewing habit.

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Oral lichen planus as a risk factor for peri-implant disease

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In this blog Rajpal Tattar looks at a review and meta-analysis investigating the correlation between oral lichen planus and peri-implant disease. Only two small observational studies were included so the availabel evidence is very limited.

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Treatment modalities in burning mouth syndrome

Depression

In this blog Manàs Dave looks at a systematic review of treatment options for patients with Burning Mouth Syndrome (BMS). Study heterogeneity means that only a narrative summary was possible so there is a need for high quality research in this area.

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Photodynamic therapy for oral lichen planus

Lichen_planusWickham's

This review looked at the efficacy of photodynamic therapy (PDT) for the treatment or oral lichen lplanus (OLP) and compares PDT with steroid therapy. 16 studies were included with the findings suggesting that photodynamic therapy may offer patients with OLP improved pain relief and better efficacy compared to topical corticosteroids.

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Digital pathology: Diagnostic concordance and discordance

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Manas Dave considers this review of the safety and reliability of digital pathology. The review included 24 studies showing high concordance between digital pathology and light microscopy suggesting that digital pathology is a viable alternative to light microscopy.

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Salivary biomarkers CYFRA 21-1 and MMP-9 for oral squamous cell carcinoma diagnosis?

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In his first blog for the Dental Elf Rajpal Tattar take a look at a review of the diagnostic accuracy of salivary biomarkers for the detection of oral squamous cell carcinoma (OSCC). The review considers two biomarkers, cytokeratin 19 fragment (CYFRA 21-1) and for matrix metalloproteinase-9 (MMP-9) but there is no conclusive evidence for either at present.

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Metastasis to the oral and maxillofacial region

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This review of metastasis to the oral and maxillofacial region included 217 studies (190 case reports,24 case series ). Metastasis were uncommon, but identified from 29 primary sites, the most common sites being lung the lungs (20.97%), breast (12.06%) and kidney (11.78%).

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Optical fluorescence imaging in oral cancer and potentially malignant disorders

leukoplakia

Manas Dave looks at a recent review of which considers the efficacy of optical fluorescence imaging as an adjunct to clinical oral examination for the detection of oral mucosal lesions. The review includes 27 studies and provides evidence to support additional high quality studies to assess its effectiveness.

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Low-level laser therapy in the prevention and treatment of oral mucositis

iStock_000001604217XSmall dental laser

Manas Dave takes a look at this review evaluating the prophylactic and therapeutic effects of low-level laser therapy (LLLT) in patients who might or have developed oral mucositis during chemotherapy or radiotherapy.

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