Curcumin for management of oral submucous fibrosis

Tumeric

This review evaluating the evidence on the effectiveness of curcumin in the management of oral submucous fibrosis included 6 small RCTs providing inconclusive evidence of a potential benefit.

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Ameloblastoma: Radical or conservative surgery?

CT_Scan_of_ameloblastoma

20 retrospective studies were included in this review of surgical approaches for ameloblastoma . The finding suggest fewer recurrences with radical approaches.

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Ameloblastoma: how common is it?

Ameloblastoma_-_high_mag

This review of the global incidence of ameloblastoma included 49 studies with just 7 studies contributing to the pooled incidence rate estimate of 0.92 per million person‐years.

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Aloe vera for treatment of oral submucous fibrosis?

shutterstock_32414035 - Betel leaf

This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Oral lichen planus and diabetes: are they associated?

Lichen_planusWickham's

This review of the relationship between oral lichen planus and diabetes included 22 studies. While both meta-analysis suggest a relationship the confidence intervals cross the line of no effect so are not statistically significant.

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Sjögren’s syndrome: treatments for dry mouth and hyposalivation

shutterstock_44704711

36 studies were included in this review of treatment options for xerostomia, hyposalivation and quality of life in patients with Sjögren’s syndrome provinding evidence to support pilocarpine use. However the number of studies were limited and adverse effects were common.

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Geographic tongue: little evidence for the management of symptomatic cases

oral_lichen

This review of treatments for the management of symptomatic benign migratory glossitis (BMG) only included 11 small low quality studies providing little evidence for the management of symptomatic BMG.

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Oral lichen planus: Rate of malignant transformation

Lichen_planusWickham's

This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.

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Mucositis in adult cancer patients reduced with keratinocyte growth factor

PDB_1qql_EBI

This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .

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Hepatitis C and oral lichen planus

HCV

This review of the association between hepatitis C virus (HCV) and oral lichen planus (OLP) identified 19 case-controlled studies. While a 6-fold increase in risk of HCV infection was noted in OLP patients a majority of the studies took place in areas with high endemic HCV rates and there is some concern regarding publication bias and the quality of the available studies.

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