This review comparing the efficacy and safety of topical antifungal drugs for oral candidiasis in children and adults included 11 RCTs 9 of which concerned adults and 2 children. The findings support the use of fluconazole and amphotericin B for adults.
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This review of the effectiveness of removable complete denture disinfection using microwaves for the treatment of denture stomatitis included 3 small RCTs. While the findings suggest that microwave may be effective the evidence is of low certainty so additional high quality well reported studies are needed.
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In this blog Manás Dave looks at a review of the prevalence of human papilloma virus (HPV) in oral potentially malignant disorders (OPMD). Although 52 studies were included one in five OPMDs being HPV positive is not a substantial link so teh findings need to be interpreted cautiously.
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This network meta-analysis of the efficacy of antifungal drugs on oral candidiasis included 31 RCTs of overal low quality suggesting that fluconazole may be the most effective.
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This review of the the efficacy of probiotics on oral Candida spp. includes 12 RCTs and suggests a possible benefit. However the quality of the evidence is limited so the findings should be intepreted cautiously.
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This review of the prevalence of oral mucosal lesions during pregnancy included 15 observational studies from 9 countries. Gingival hyperplasia was most commonly report however the quality of the available evidence was assessed as very low.
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