Dentine Hypersensitivity: Which agents are most effective?

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This review of treatments used to treat dentine hypersensitivity. 254 different agents were tested with all showing some effectiveness in short term.

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Desensitising toothpastes for dentine hypersensitivity a network meta-analysis

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This network meta-analysis comparing the effect of different desensitising toothpastes on dentine hypersensitivity included 30 RCTs. The findings suggest that toothpastes containing nano-hydroxyapatite or arginine may be the most effective. However additional larger studies are required.

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Dentine hypersensitivity: Effectiveness of desensitising toothpastes

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This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.

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Arginine and caries prevention

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7 RCTs were included in this review of the caries prevention effects of arginine containing dental products. They provide insufficient evidence to support a caries preventive effect for arginine in toothpaste.

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Arginine in combination with calcium bases and fluoride in toothpaste may be better than fluoride alone

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Ten trials were included in this review of arginine in toothpaste. It found that arginine in combination with calcium bases (either Dical or calcium carbonate) and fluoride provided a superior effect compared with fluoride alone. However, 9 out of 10 of the trials were sponsored by a single company and the overall quality of the evidence was considered to be low.

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Dentine hypersensitivity: which treatments are best?

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This review of dentine hypersensitivity treatment was broad, covering 11 agents and 105 RCTs. Most treatments suggested some benefits but the quality of available evidence was limited and there was little information on the relative effectiveness of the various agents.

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Dentine hypersensitivity following periodontal treatment reduced by use of desensitising paste

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In this small trial the use of either an 8% arginine desensitising paste or prophy paste reduced dentine hypersensitivity after scaling but the arginine base paste was significantly better than the standard prophy paste.

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Dentine hypersensitivity: most desensitising toothpastes provided benefit finds review

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31 RCTs were identified for this review of desensitising toothpastes for dentine hypersensitivity. A wide range of agents were tested and most were found to be effective although the number of trials available for each agent was relatively small range from 3-8 studies.

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Study suggests that dentifrices containing 1.5% arginine, an insoluble calcium compound provides additional benefit to fluoridated toothpastes

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Cochrane reviews have clearly documented the anti-caries benefits of fluoridated toothpastes (Marhino et al 2003, Walsh et al 2010). New agents to improve caries prevention would assist efforts to reduce the impact of caries, particularly on children. The aim of this study was to investigate the efficacy of two dentifrices containing 1.5% arginine, an insoluble [read the full story…]

New study suggests better outcomes with arginine toothpaste and mouthwash regimen for dentine hypersensitivity treatment.

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Earlier this month (Dental Elf 18th Feb) we looked at a systematic review of the use of arginine toothpastes to reduce dentine hypersensitivity.   A new study is now available which compares arginine toothpaste, potassium nitrate toothpaste against a standard fluoride toothpaste. Adult patients with at least two hypersensitive teeth were randomised to one of three [read the full story…]