Acute pain management following dental extraction

volodymyr-hryshchenko-m1Hq4ibP9rc-unsplash

This review and network meta-analysis (NMA) of pharmacological treatments for the management of pain subsequent to simple and surgical tooth extraction included 85 RCTs. There was moderate- and high-certainty evidence that for surgical dental extractions that ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg was the most effective for pain relief.

[read the full story...]

Oxycodone for acute dental pain?

shutterstock_32144176

This review of the efficacy of oxycodone for post-operative acute dental pain included 13 studies. the findings showed that NSAIDs are generally superior for post-surgical dental pain, with a better adverse effect profile,so the need for oxycodone in dentistry is limited.

[read the full story...]

Pulpal anaesthesia for symptomatic irreversible pulpitis in mandibular molars

shutterstock_17571817- injection

Colin Levey takes a look at this network meta-analysis of 46 RCTs assessing techniques and drugs for achieving pulpal anaesthesia for the non-surgical endodontic treatment of mandibular molars.

[read the full story...]

Prescription drug misuse in women: US review inconclusive

31930243468_b6056a2969_h

Rob Poole writes his debut elf blog on a recent systematic review of trends in prescription drug misuse among women, which finds a mixed and complex picture with few conclusive findings.

[read the full story...]

The US opioid crisis: quantifying the impact

Prescription opioids

Emma Wincup examines a recent US cross-sectional study that measures the burden of opioid-related mortality in the United States, which suggests that opioids (prescribed and illicit) could kill nearly half a million people across America over the next decade.

[read the full story...]

Inferior Alveolar Nerve Block: improving anaesthetic success in patients with irreversible pulpitis

shutterstock_17571817- injection

This network meta-analysis of oral premedication to improve anaesthetic success of inferior alveolar nerve block in patients with irreversible pulpitis suggest that that oral premedication with dexamethasone, NSAIDs and Tramadol increases the success rate.

[read the full story...]

Non-medical use of prescription drugs #NonMedicalDrugs

playmobil-451203_1280

Ian Hamilton and Julia Buxton from the University of York preview the #NonMedicalDrugs event that will take place in York on Friday 16th March 2018.

The meeting will bring together people who can offer personal and professional insights of the extent of the issue and how we can support people who develop problems.

[read the full story...]

Opiate substitution therapy: supervised-consumption vs take-home doses

methadone

Vicky Carlisle publishes her debut elf blog on a Cochrane review of supervised dosing with long-acting opioid medication in the management of opioid dependence.

[read the full story...]

Few adverse events with single dose oral analgesics for acute postoperative pain

This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.

[read the full story...]

Impaired inhibitory control in addiction

shutterstock_153140405

Maartje Luijten, Assistant Professor at the Behavioural Science Institute at Radboud University, writes her debut blog on a recent meta-analysis of deficits in behavioural inhibition in substance abuse and addiction.

[read the full story...]