Orofacial pain: pharmacological treatments

The authors sought to review available literature relating to SSRI withdrawal syndromes

This review of pharmacological management of orofacial pain included 41 studies. Evidence suggests that for TMD joint pain NSAIDs, corticosteroids and hyaluronate injections are beneficial and that clonazepam and capsaicin are effective for burning mouth syndrome.

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Prednisolone for post-endodontic pain?

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This randomised controlled trial of a single, preoperative oral dose of prednisolone on post-endodontic pain involved 400 patients demonstrating a significant reduction in pain at 6,12 and 24 hours.

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Endodontic pain can be managed with non-steroidal anti-inflammatory drugs

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This review of the use of non-steroidal anti-inflammatory drugs (NSAIDs) for the management of post endodontic pain demonstrates that they do help to manage the pain.

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Endodontic postoperative pain: which non-steroidal anti-inflammatory drug?

This RCT does not establish equivalence between mindfulness-based cognitive therapy and antidepressants for recurrent depression.

The review of NSAIDs for endodontic postoperative pain suggests that NSAIDs are effective. A combination of ibuprofen 600 mg and acetaminophen 1000 mg and Ibuprofen 600 mg were both effective. More studies are need to assess teh most effective NSAIDs dosages and does intervals.

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Pain during orthodontic treatment: non-pharmacological interventions

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14 trials were included in this Cochrane review of non-pharmacological interventions for orthodontic pain. The findings were inconclusive although there is some evidence that low-level laser therapy may help.

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Gingivitis: anti-inflammatory agents may be beneficial suggests review

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A new review of anti-inflammatory agents for the management of gingivitis identified 14 studies. While the various anti-inflammatory agents showed benefit, the majority of the studies were at high risk of bias, so the results should be treated with caution.

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On-demand analgesic use following root canal treatment resulted in similar pain relief but reduced consumption compared with regular prescription

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The management of pre- and post-operative pain is a key component of endodontic treatment with studies reporting that the incidence of post operative pain (flare-up) ranges from  3-58%.   Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common medication used for managing pain after root canal treatment (RoCT). The aim of this study was to compare the [read the full story…]

Ibuprofen more effective than paracetamol for postoperative pain following third molar removal

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Surgical removal of third molars is a very common procedure and postoperative pain is a major concern for patients. Non-steroidal anti-inflammatory drugs are (NSAIDs) frequently recommended to manage this pain.   Ibuprofen and paracetamol commonly used and recently a combination analgesic containing both paracetamol and ibuprofen has become available in the UK. The aim of this [read the full story…]

Small study found that pre-operative ibuprofen improved efficacy of inferior alveolar nerve blocks

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Inferior alveolar nerve block (IANB) is a routine technique for achieving regional anaesthesia. However, it is not always successful, with inflammation being a potential cause.  The aim of this study was to evaluate the effect of preoperative oral ibuprofen (IBU) on the success of inferior alveolar nerve blocks (IANBs) with mepivacaine containing 1: 100 000 epinephrine for [read the full story…]

Taking ibuprofen before wisdom tooth removal does not appear to be more effective for controlling post operative pain

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The removal of lower third molars is one of the commonest surgical procedures. The effective management of post operative pain is an important consideration and it has been suggested that preoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) may be more effective than post operative administration. The aim of this study was therefore to compare the [read the full story…]