Risperidone and aripiprazole: genotype, metabolism and dosage

CYP2D6 genotyping before starting treatment might be valuable in clinical practice for individualising risperidone and aripiprazole treatment.

Dolly Sud writes her debut elf blog on a recent retrospective analysis, which compares dose changes of risperidone and aripiprazole with patients’ individual genotype.

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Focus of pharmacotherapy for people with learning disabilities and mental ill health should be on specific forms of psychopathology


A number of studies have suggested that prevalence rates of mental ill-health in people with learning disabilities is higher than in the general population, although issues of definition have made it difficult to make clear comparisons. The authors of this review set out to identify trends and developments in the study of psychopathology in people [read the full story…]