Can preventing childhood maltreatment reduce depression?

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Researchers pulled together evidence from more than half a million people to test a simple but important idea: if childhood maltreatment raises the risk of adult depression, could reducing maltreatment help prevent it? The answer, as always, is more complicated than it first appears.

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Adolescent versus adult depression: Is risk of recurrence the same?

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Is teenage depression more likely to come back later in life? A new population study challenges assumptions and finds similar recurrence risks in both adolescents and adults.

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Ketamine, depression and childhood trauma: new evidence from a community study

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Can ketamine help people with treatment-resistant depression, regardless of childhood trauma history? This new study suggests that trauma load and severity may not influence treatment outcomes.

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Immersive virtual reality for the treatment of mental health disorders: anxiety leads the way

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Rena Gatzounis blogs about a systematic review and meta-analysis investigating the effectiveness of immersive virtual reality treatments for mental health disorders.

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The rapid increase in global mental illness: fake news?

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A group of UCL Mental Health Masters students summarise a systematic review and meta-analysis examining if the global prevalence rate of adult mental illness is increasing.

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Risk factors for suicide in people with bipolar disorder

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Dafni Katsampa explores a recent prospective cohort study of risk factors for suicide in bipolar disorder, which finds significant variation in risk factors in men and women.

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Inhaling evidence about tobacco and psychosis

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Ian Hamilton explores a recent Finnish study of adolescent tobacco smoking and the risk of psychosis, which found that young people aged 15-16 who smoked more than 10 cigarettes a day were three times more likely to have psychosis by the time they reached age 30.

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Suicide risk following childhood interpersonal violence

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Katrina Witt considers the findings of a meta-analysis of longitudinal studies, which looks at exposure to interpersonal violence in childhood, and the impact that it may have on risk of suicide in young people.

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Polypharmacy for major depression: is practice evidence-based?

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Jessica Bone reports on a recent cross-sectional study that looks at the clinical correlates of augmentation/combination treatment strategies in major depressive disorder.

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Risk factors and peripheral biomarkers for schizophrenia spectrum disorders

This 'umbrella review' aimed to systematically appraise the meta-analyses of observational studies on risk factors and peripheral biomarkers for schizophrenia spectrum disorders.

Marcus Munafo considers the findings of a systematic review of meta-analyses of observational studies, which looks at risk factors and peripheral biomarkers for psychotic disorders on the schizophrenia spectrum.

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