depression

Depression is a serious illness. Health professionals use the words depression, depressive illness or clinical depression to refer to it. It is very different from the common experience of feeling unhappy, miserable or fed up for a short period of time. When you are depressed, you may have feelings of extreme sadness that can last for a long time. These feelings are severe enough to interfere with your daily life, and can last for weeks or months, rather than days. Depression is quite common and about one in ten people will experience depression at some point. However, the exact number of people with depression is hard to estimate because many people do not get help or are not formally diagnosed with the condition.

Our depression Blogs

Could partner factors reduce the risk of maternal depression and anxiety in the perinatal period?

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Paul Ramchandani and Ellen Grimas report on the findings of a recent systematic review and meta-analysis of modifiable partner factors associated with perinatal depression and anxiety.

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Combined methylphenidate and citalopram may help older people with depression recover faster

Depressed older man

Lisa Burscheidt summarises a recent randomised controlled trial of combined methylphenidate and citalopram for depression in older people, which presents promising but limited findings.

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Antidepressants for depression in cancer: Cochrane review highlights lack of evidence

Female cancer patient

Kirsten Lawson reports on a recent Cochrane systematic review, which highlights a lack of high quality trials about the efficacy and safety of antidepressants for depression in cancer.

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Cognitive or behavioural components in group therapy for people with mild learning disabilities and depression?

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There is a growing evidence base that with the right modifications, people with learning disabilities can benefit from cognitive behavioural approaches to treating depression.

Here, Rose Tomlins looks at a study which looked at the impact of cognitive, behavioural or joint strategies.

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Psychodynamic therapy: time for a new approach?

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Mark Smith summarises a recent narrative review about the effectiveness of psychodynamic therapy for depression, anxiety disorders, eating disorders, somatic disorders and other mental health conditions.

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Mood Matters: mood instability is common and associated with poor outcomes

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Farhana Mann summarises an observational study of mood instability in people with mental illness, which explores its relationship with days spent in hospital, frequency of admissions, the likelihood of being sectioned and the chance of being prescribed antipsychotics and mood stabilisers.

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Joining the dots: mental and physical health

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Lia Ali and colleagues from the IMPARTS project present the findings of their group discussions about a recent review of mortality in mental disorders. Along the way she discusses the staff training they carried out and the tweet chat they ran to consider the implications of this research, both to individuals and on the global burden of disease.

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Psychotherapies for depression in children and young people

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Shirley Reynolds considers the findings of a recent network meta-analysis, which investigates the comparative efficacy and acceptability of psychotherapies for depression in children and adolescents.

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Crisis of faith? Instead of CBT, we should be worrying about meta-analyses

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Ioana Cristea appraises a recent meta-analysis, which examines whether the treatment effects of CBT have decreased over time. She finds a study with such significant limitations, that her blog ends up questioning the objectivity and reliability of meta-analyses.

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Does cCBT hold promise for the treatment of depression and anxiety in youth?

Teenage boy using laptop

Andres Fonseca appraises and summarises two recent meta-analyses of computerised therapies (including cCBT) for anxiety and depression in children and young people.

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