Results: 305

For: depression

Dose equivalents of antidepressants: standardising prescribing between different drugs

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Andrew Shepherd summarises a meta-analysis, which looks at the dose equivalents of antidepressants by bringing together data from 83 trials of 23 different antidepressants.

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Another negative trial of cognitive bias modification: a case for Occam’s razor

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Ioana Cristea reviews a recent RCT that found no effects of positive imagery-based cognitive bias modification, delivered as a web-based treatment for people with depression.

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Mindfulness-based cognitive therapy to prevent depression

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André Tomlin presents the results of the PREVENT RCT published today in The Lancet, which investigates the effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence.

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Varenicline and the risk of neuropsychiatric adverse events and death

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Natasha Clarke publishes her debut Mental Elf blog about a new systematic review and meta-analysis investigating the risk of neuropsychiatric adverse events associated with the smoking cessation drug varenicline.

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Do we stigmatise mental illness more as we age?

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Raluca Lucacel writes her debut blog about an age-period-cohort analysis, which investigates how attitudes towards people with mental illness worsen during the course of life.

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The antidepressant effects of ketamine are confirmed by a new systematic review and meta-analysis

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Helge Hasselmann summarises a new systematic review and meta-analysis, which confirms the antidepressant effects of ketamine.

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Antidepressant withdrawal syndromes: time to grasp the nettle?

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Andrew Shepherd appraises and summarises a systematic review of antidepressant withdrawal symptoms after SSRI discontinuation, which leads him to reconsider his own clinical practice.

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Depression to blame for violent crime? The curse of the headline writers

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Laurence Palfreyman highlights a population study from researchers at Oxford University, which investigates the links between depression and violent crime. The study finds that people with depression were three times more likely to have been convicted of violent crime than those without depression, but we need to be careful about how we interpret these relative risk figures.

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Limited benefits of cognitive bias modification for adolescents: is it time to move on?

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Ioana Cristea reviews a recent randomised controlled trial of cognitive bias modification to treat interpretation bias in adolescents. She argues that this new study adds weight to the ascertion that there are very limited, if any, mental health benefits for CBM interventions.

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Cognitive bias modification for anxiety and depression in children and adolescents

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Shirley Reynolds writes her debut Mental Elf blog on a recent meta-analysis of cognitive bias modification (CBM) for anxiety and depression in children and adolescents. The review suggests that, on the face of it, we should not be investing in future CBM research, but is it that simple?

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